For more than a century there has been awareness of the fact that the eye is not a perfect optical system and that it suffers optical aberrations other than defocus and astigmatism. Optical aberrations in the human eye impose a major physical limit on vision .Customized ablation is an ablation pattern that attempts to optimize the eye’s highly sophisticated optical system based on the individual eye’s optics and anatomy, as well as the patient’s needs.There are two forms of customization,the first measures the wavefront error of the entire eye and treats based on these measurements while the second measures the ocular aberrations detected by corneal topography .Wavefront analysis is a promising technology that provides an advanced method for measuring optical distortions in the eye. Measuring and treating these distortions goes beyond nearsighted, farsighted, and astigmatism determinations that have been used for centuries. As a result, physicians can now customize the refractive procedures according to each individual patient’s unique vision correction needs. The treatment is unique to each eye, just as a fingerprint is unique. Applications of wavefront-guided ablation are myopia, asymmetrical ablation after laser, post-LASIK night vision complaints, irregular astigmatism, optimizing IOL and contact lenses.