Serum Troponin-IAs A Prognostic Marker In Acute Exacerbated Chronic Obstructive Pulmonary Disease Patients

Introduction: Chronic obstructive pulmonary disease (COPD) is a disease characterized by airflow limitation that is not fully reversible. The airflow limitation is usually both progressive and associated with an abnormal inflammatory response of the lungs to noxious particles or gases and associated with systemic manifestations. Exacerbation of COPD is an event in the natural course of the disease and affects the quality of life and prognosis of patients. The spectrum of cardiovascular complications associated with COPD is clearly broad, Right ventricular (RV) dysfunction and pulmonary vascular disease are common in COPD and progress with time. Other cardiac diseases found frequently in patients with COPD, including coronary artery disease (CAD) and arrhythmias. In RV failure, cardiac Troponins are suspected to be elevated secondary to RV ischemia or micro infarction resulting from an increased wall tension, metabolic demand, and reduced coronary perfusion with or without atherosclerosisAim of the Work: This work aimed to evaluate the prognostic value of Troponin I level in acute exacerbated chronic obstructive pulmonary diseases (AECOPD) and its impact on the hospital outcome in those patients.