New Advances in Diagnosis and Treatment of Stress Incontinence in Females

Stress urinary incontinence (SUI) is the most common type of incontinence in women. SUI is defined by the International Continence Society (ICS) as the complaint of involuntary leakage of urine on effort or exertion, or on sneezing or coughing.Stress incontinence is classified into two types: urethral hypermobility (type I) and intrinsic sphincter deficiency (ISD) (type II).Diagnosis of stress urinary incontinence depends mainly on the full detailed history to determine the severity. Urodynamic tests may help in diagnosis and determine the type of stress incontinenceThe mid-urethral sling remains the best studied, prospectively and retrospectively, incontinence therapy known. The midurethral TVT and TOT slings are effective treatments of female stress urinary incontinence, with high rates of short- and long-term efficacy, in addition to a low complication and side effect profile.Overall, injection therapy for stress incontinence is easy to perform, minimally morbid, convenient for the patient, and remains very cost-effective, especially when performed in the outpatient office setting. Autologous Muscle-Derived Cells and Adipose derived Stem Cells. Pure injection therapy may be a promising treatment to restore urethral sphincter function.The question arises, however: has colposuspension had its day with the introduction of TVT and other midurethral tapes?The results of the present study showed a significant decrease in TSB, TAC, Serum uric acid, Vitamin C concentration, Serum albumin and malondialdehyde after phototherapy than before it. There was also a significant negtive correlation between MDA and TAC.Recommendations:Further Studies are recommended including:1. Study the role of antioxidants in management of neonatal hyperbilirubinemia.2. Study the lipid peroxidation markers and antioxidant activity in relation to phototherapy.