Murine Double Minute in Cases of Non- Hodgkin’s Lymphoma

This essay devoted to find the role of MDM2 in non Hodgkin’s lymphoma by knowing its pathogenesis.Mdm2 protein has been shown to interact with a large number of cellular proteins besides p53. Although the exact function and significance of these interactions are not fully understood, the p53-independent functions of Mdm2 may have a role in cancer etiology and progression, indicating that the MDM2 oncogene is a potential molecular target for cancer therapy. The study of cellular functions that are involved in the oncogenic properties of MDM2 is an important topic for future research that should help in the development of new therapeutics against cancer.