| Abstract: |
Gene therapy is a technique for correcting defective genes responsible for disease development. Researchers may use several approaches for correcting faulty genes the most common approach is the insertion of normal gene into a nonspecific location within the genome to replace a nonfunctional gene.A carrier molecule called a vector must be used to deliver the therapeutic gene to the patient’s target cells. Currently, the most common vector is a virus that has been genetically altered to carry normal human DNA. Besides virus-mediated gene-delivery systems, there are several nonviral options for gene delivery. Some of them depend on the physical (carrier-free gene delivery) approach and the others depend upon chemical approaches (synthetic vector-based gene delivery). Gene therapy is a tool that could be used in treatment and prevention of different diseases in all body systems like cancer, ischemic heart diseases. Neurodegenerative disorders and diabetes mellitus.
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