THE ROLE OF GROWTH FACTORS IN THE DEVEOLPMENT OF DIABETIC KIDNEY DISEASE

AbstractDiabetic nephropathy is one of the most serious complications of diabetes and the most common cause of end-stage renal failure in the world. Recently, various clinical studies have been published dealing with possible correlations between serum or urinaryGH/IGF-1 levels and kidney function in type 1 diabetic patients. Pre-pubertal microalbuminuric patients had higher levels of urinary GH and urinary and plasma IGF_1 than normoalbuminuric diabetic and control subjects