Three-Component Process for the Synthesis of Pyrimido[2,1-c][1,2,4]triazine Derivatives via Knoevenagel Condensation Under Thermal Aqueous Conditions

Faculty Science Year: 2015
Type of Publication: ZU Hosted Pages:
Authors:
Hossam Aly Hussein Saad
Journal: Current Organic Synthesis Bentham pub. Volume:
Keywords : Three-Component , Process , , , , , Synthesis , , , Pyrimido[2,1-c][1,2,4]triazine , Derivatives , Knoevenagel    
Abstract:
Abstract: A Knoevenagel one-pot synthesis of 6-amino-4-oxo-8-(2-thienyl)-3-[2-(2-thienyl)vinyl]-4H-pyrimido[2,1- c][1,2,4]triazine-7-carbonitrile 2 via the reaction of 3-amino-6-[2-(2-thienyl)vinyl]-1,2,4-triazin-5(4H)-one 1 with thio
    
     
 
       

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  • Hossam Aly Hussein Saad, "Charge transfer complexation of the anticholinergic drug clidinium bromide and picric acid in different polar solvents: Solvent effect on the spectroscopic and structural morphology properties of the product", Elsevier, 2016 More
  • Hossam Aly Hussein Saad, "THIOSEMICARBAZIDES, POTENT REAGENTS FOR SYNTHESIS OF SOME NEW 1,4-DIPHENYLBENZO[g]QUINOXALINE-5,10-DIONE BASED HETEROCYCLES", Elsevier, 2016 More
  • Hossam Aly Hussein Saad, "Spectrophotometric and thermodynamic studies on the 1:1 charge transfer interaction of several clinically important drugs with tetracyanoethylene in solution-state: Part one", Elsevier, 2016 More
  • Hossam Aly Hussein Saad, "Charge-Transfer Complexes of Two Highly Efficient Drugs with σ- and π-Acceptors: Spectroscopic, Thermal, and Surface Morphology Characteristics", Springer, 2016 More

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