Click reaction based synthesis, antimicrobial, and cytotoxic activities of new 1,2,3-triazoles

Faculty Science Year: 2015
Type of Publication: ZU Hosted Pages:
Authors:
Hossam Aly Hussein Saad
Journal: Bioorganic & Medicinal Chemistry Letters Elsevier Ltd. Volume:
Keywords : Click reaction based synthesis, antimicrobial, , cytotoxic    
Abstract:
Three-motif pharmacophoric models 20a–e and 21–25 were prepared in good yields by CuAAC of two azido substrates 2 and 11 with seven terminal acetylenic derivatives including chalcones 17a–e, theo- phylline 18 and cholesterol 19. The structu
    
     
 
       

Author Related Publications

  • Hossam Aly Hussein Saad, "Charge transfer interaction of organic p-acceptors with the anti-hyperuricemic drug allopurinol: Insights from IR, Raman, 1H NMR and 13C NMR spectroscopies", Publisher: Croatian Pharmaceutical Society,, 2016 More
  • Hossam Aly Hussein Saad, "Charge transfer complexation of the anticholinergic drug clidinium bromide and picric acid in different polar solvents: Solvent effect on the spectroscopic and structural morphology properties of the product", Elsevier, 2016 More
  • Hossam Aly Hussein Saad, "THIOSEMICARBAZIDES, POTENT REAGENTS FOR SYNTHESIS OF SOME NEW 1,4-DIPHENYLBENZO[g]QUINOXALINE-5,10-DIONE BASED HETEROCYCLES", Elsevier, 2016 More
  • Hossam Aly Hussein Saad, "Spectrophotometric and thermodynamic studies on the 1:1 charge transfer interaction of several clinically important drugs with tetracyanoethylene in solution-state: Part one", Elsevier, 2016 More
  • Hossam Aly Hussein Saad, "Charge-Transfer Complexes of Two Highly Efficient Drugs with σ- and π-Acceptors: Spectroscopic, Thermal, and Surface Morphology Characteristics", Springer, 2016 More

Department Related Publications

  • Mohamed Gamal Helmy Mohamed Abdelwahed, "Electronic Properties of Organic Complexes. 2. Reactive Azodyes", Spain, 1993 More
  • Mohamed Gamal Helmy Mohamed Abdelwahed, "Electrical Behaviour of some Azodye Mixed Ligand with Gd3+ and Er3+. b", Peru, 1994 More
  • Atef Mohamed AbdelHamid Ali Hassn, "heterocyclization of thiouracil derivative: synthesis of thiazolopyrimidines, tetrazolopyrimidines and triazolopyrimidines of potential biological activity", elsevier, 2015 More
  • Mohammed Aref Awad Allah Abu Zyd, "Synergistic positive effects of nano barium silicate on the hydration rate and phase composition of alkali-activated slag", Elsevier, 2022 More
  • Ahmed Abdelmoniem Ahmed Amer, "Synthesis and characterization of some calcium aluminate phases from nano-size starting materials", 0366-3175/© 2020 SECV. Published by Elsevier Espana, ˜ S.L.U, 2020 More
Tweet