Synthesis, antimicrobial and cytotoxicity evaluation of new cholesterol congeners

Faculty Science Year: 2015
Type of Publication: ZU Hosted Pages:
Authors:
Hossam Aly Hussein Saad
Journal: Beilstein J. Org. Chem. UK Volume:
Keywords : Synthesis, antimicrobial , cytotoxicity evaluation , , cholesterol congeners    
Abstract:
3β-Azidocholest-5-ene (3) and (3β)-3-(prop-2-yn-1-yloxy)cholest-5-ene (10) were prepared as substrates to synthesize a variety of three-motif pharmacophoric conjugates through CuAAC. Basically, these conjugates included cholesterol and 1,2,
    
     
 
       

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