Synthesis, antimicrobial and cytotoxicity evaluation of new cholesterol congeners

Faculty Science Year: 2015
Type of Publication: ZU Hosted Pages:
Authors:
Hossam Aly Hussein Saad
Journal: Beilstein J. Org. Chem. UK Volume:
Keywords : Synthesis, antimicrobial , cytotoxicity evaluation , , cholesterol congeners    
Abstract:
3β-Azidocholest-5-ene (3) and (3β)-3-(prop-2-yn-1-yloxy)cholest-5-ene (10) were prepared as substrates to synthesize a variety of three-motif pharmacophoric conjugates through CuAAC. Basically, these conjugates included cholesterol and 1,2,
    
     
 
       

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  • Hossam Aly Hussein Saad, "THIOSEMICARBAZIDES, POTENT REAGENTS FOR SYNTHESIS OF SOME NEW 1,4-DIPHENYLBENZO[g]QUINOXALINE-5,10-DIONE BASED HETEROCYCLES", Elsevier, 2016 More
  • Hossam Aly Hussein Saad, "Spectrophotometric and thermodynamic studies on the 1:1 charge transfer interaction of several clinically important drugs with tetracyanoethylene in solution-state: Part one", Elsevier, 2016 More
  • Hossam Aly Hussein Saad, "Charge-Transfer Complexes of Two Highly Efficient Drugs with σ- and π-Acceptors: Spectroscopic, Thermal, and Surface Morphology Characteristics", Springer, 2016 More

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