Urinary leukotriene level in patients with bronchial asthma

The aim of this study is to measure urinary leukotriene E4 levels in patients with bronchial asthma in comparison to control subjects and to define a potential role of Cys LTs in patients with bronchial asthma. The results of this study elucidated that:1- Pollen was the most common allergen found to cause +ve skin test in patients (63.41% of cases) followed by smoke (53.65%).2- The mean values of blood eosinophilic percentage, urinary LTE4 and total IgE level of patients were significantly higher than that of control group.3- The mean values of blood eosinophilic percentage, urinary LTE4 and total IgE level of atopic patients was higher than that of non- atopic patients although the difference was not statistically significant.4- The mean values of blood eosinophilic percentage, urinary LTE4 and total IgE level were higher in male patients than those of female patients although the difference was not statistically significant.5- There were positive significant correlations between blood eosinophilic percentage, urinary LTE4 and total IgE level of patients.6- There were no correlations between age of patients and blood eosinophilic percentage, urinary LTE4 and total IgE level.7- There were no correlations between duration of illness of patients and blood eosinophilic percentage, urinary LTE4 and total IgE level..