Correlation Between Serum Level Of Progesterone, Beta-Human Chorionic Gonadotropin And Karyotype Of The Product Of Conception In Repeated Early Fetal Losses

Recurrent abortion is classically defined as three or more consecutive pregnancy losses, although recently more than two pregnancy losses including those which are not consecutive are also considered as recurrent abortions (Rubio, et al., 2005). This condition affects approximately 1% of the couples at reproductive age and even after an appropriate work-up, almost 50% of cases remain classified as of unknown etiology (Li et al., 2002). Therefore, recurrent pregnancy losses still constitute a major dilemma for many obstetricians and infertility specialists. It remains a major area of research in many centers involved in reproduction and immunology. In spite of the constant research on the subject, the causes and treatment of recurrent abortion are still a bewildering subject to the clinician (Rubio, et al., 2005).To establish the possible correlation between karyotype of anembryonic and embryonic first trimester pregnancies and serum levels of -hCG and progesterone at the time of surgical termination of pregnancy from patients with spontaneous loss, that were neither under hormonal stimuli nor in assisted reproduction studies.