Study of the role of paraoxonase enzyme activity in vascular complications of non-insulin dependent diabetes mellitus

this study is designed to investigate the activity ofparaoxonase enzyme in diabetics and try to find out a relationshipbetween this activity and diabetic vascular complications.This study included a total number of 66 subjects, they wereclassified into:Group I: Control group included 15 healthy volunteers.Group II: Diabetic group included 51 diabetic patient. Afterscreening of diabetic vascular complications they weresubdivided into:Group IIA: included 15 NIDDM patients not suffering fromdiabetic microvascular or macrovascularcomplications.Group lIB: included 21 NIDDM patients with diabetic retinopathy.According to the severity of retinopathy they were subdivided into :Group lIB]: included 7 NIDDM patients with background diabeticretinopathyGroup IIB2: included 7 NIDDM patients with preproliferativediabetic retinopathy.Group IIB3: included 7 NIDDM patients with proliferative diabeticretinopathy.Group Il’C: included 15 NIDDM patients suffering from hemiplegiaand had cerebrovascular stroke.