Injection Sclerotherapy For Bleeding Oesophageal Varices In Childern With Or With Out Octerotide

Portal hypertension is a common and serious problem in children,various portosystemic collateral channels develop as a result of portalhypertension.Oesophageal varices develop as a result of portal hypertension, andbleeding oesophageal varices is a major complication. EndoscopicI.sclerotherpay, and pharmacologic vasoactive drugs are used for propercontrol of acute bleeding episodes; prevention of early rebleeding, and ineradication of oesophageal varices.The aim of the present study was to evaluate the efficacy of injectionsclerotherapy in control ofacute bleeding in comparison with the additionaluse of octerotide for proper control of acute bleeding and prevention of_......-- early rebleeding, also to evaluate the efficacy of sclerotherpay on varicealeradication and prevention of recurrence.The study comprised 40 children who were divided into 2 groups.All children had oesophageal varices as detected by upper gastrointestinalendoscope. The first group, 20 children subjected to endoscopicsclerotherapy only while second group subjected to combined injection;.sclerotherapy and octerotide infusion for 3 days after sclerotherpay sessionin a dose of 1 ug/kg/hour.All cases of the 2 groups were subjected to the followinginvestigations:• Complete blood count.• Liver function test.- ’.• Prothrombin time.Hepatitis markers including hepatitis B surface antigen and hepatitis Cantibodies.Liver biopsy for selected cases.Doppler ultrasound.Abdominal ultrasound.