Zagazig University Digital Repository
Home
Thesis & Publications
All Contents
Publications
Thesis
Graduation Projects
Research Area
Research Area Reports
Search by Research Area
Universities Thesis
ACADEMIC Links
ACADEMIC RESEARCH
Zagazig University Authors
Africa Research Statistics
Google Scholar
Research Gate
Researcher ID
CrossRef
Functional Platform for Controlled Subcellular Distribution of Carbon Nanotubes
Faculty
Pharmacy
Year:
2011
Type of Publication:
Article
Pages:
9264-9270
Authors:
Serag, Maged F, Kaji, Noritada, Tokeshi, Manabu, Bianco, Alberto, Baba, Yoshinobu, Venturelli, Enrica, Okamoto, Yukihiro, Terasaka, Kazuyoshi, Mizukami, Hajime, Braeckmans, Kevin
DOI:
10.1021/nn2035654
Journal:
ACS NANO AMER CHEMICAL SOC
Volume:
5
Research Area:
Chemistry; Science \& Technology - Other Topics; Materials Science
ISSN
ISI:000297143300091
Keywords :
plant cell, single-walled carbon nanotubes, fluorescein isothiocyanate, diffusional mobility, subcellular distribution
Abstract:
As nanoparticles can cross different cellular barriers and access different tissues, control of their uptake and cellular fate presents a functional approach that will be broadly applicable to nanoscale technologies in cell biology. Here we show that the trafficking of single-walled carbon nanotubes (SWCNTs) through various subcellular membranes of the plant cell is facilitated or inhibited by attaching a suitable functional tag and controlling medium components. This enables a unique control over the uptake and the subcellular distribution of SWCNTs and provides a key strategy to promote their cellular elimination to minimize toxicity. Our results also demonstrate that SWCNTs are involved in a carrier-mediated transport (CMT) inside cells; this is a phenomenon that scientists could use to obtain novel molecular insights into CMT, with the potential translation to advances in subcellular nanobiology.
Online
PDF
جامعة المنصورة
جامعة الاسكندرية
جامعة القاهرة
جامعة سوهاج
جامعة الفيوم
جامعة بنها
جامعة دمياط
جامعة بورسعيد
جامعة حلوان
جامعة السويس
شراقوة
جامعة المنيا
جامعة دمنهور
جامعة المنوفية
جامعة أسوان
جامعة جنوب الوادى
جامعة قناة السويس
جامعة عين شمس
جامعة أسيوط
جامعة كفر الشيخ
جامعة السادات
جامعة طنطا
جامعة بنى سويف