Study of Red Cell creatine level in cases of thalassemia

Diagnosis of a haemolytic disease usually requirescar.eful analysis of the findings that pertain to redcell production and red cell destruction rates.The widely used laboratoy tests aimed at uetectingincreased breclcdOMl products of red cell allow at besta rough quantitative estimation of the intensity of thehaemolytic process, and thes tests are influenced bymany factors • For instance, hyperbilirubinaemia maybe inappropriately increased by an accampanying liverdysfunction, and the haptoglobin level may be raisedunspecifically during an inflamatory process owing tothe fact that .these indices of increased breackdown ofred cells are relatively imprecise, the intensity ofa haemolytic process is assessed mainly by its comp-ansatory increase in red cell production.