anaesthesia and diseased kidney

bbefore considering the effects of anaesthesia on the kidney, it is necessary to briefly review the applied anatomy and physiology of the kidney.this includes an account of renal blood flow, glomerular filtration rate, juxtaglomerular apparatus, renal auto-regulation and intra-renal blood flow distribution, tubular transport mechanisms, solute handling in proximal tubule, function of loop of henle and distal tubule system.