| Abstract: |
Prostaglandins (PGS) are known to play an important role in allergic1. Abrams’ needle biopsy should never be neglected as an invaluable diagnostic tool in the diagnosis of exudative pleural effusion that never to be abandoned.2. Based on routine investigations and clinical suspicions, the priority of CT-guided or blind Abrams’ pleural biopsies should be individualized as shown in the following algorithm (fig-11).3. Multiple CT-guided cutting needle pleural biopsies are advisable to be tried in patients with exudative pleural effusion as this guided technique may improve the total sensitivity of this procedure.4. The conclusion of the current study should be challenged widely on larger groups of patients for each of the items included.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.In laryngeal expansion surgery for subglottic and tracheal stenosis, after vertically dividing the stenotic segment in the midline and insertion of graft material between the divided segments, either prolonged stenting with tracheostomy (4-6 weeks) or short-term stenting using endotracheal tube with sedation or mechanical ventilation (1-2 weeks) is required until the airway is stabilized. The postoperative period is far more difficult and requires meticulous skillful care. This experimental study was designed to explore the use of microplates and auricular cartilage graft in providing immediate airway stability and to determine the surgical outcome of this procedure. Subglottic stenosis was ceriated in 11 dogs using repeated abrasive technique to the mucosa and perichondrium. All 11 dogs underwent laryngotracheal reconstruction without intraoperative complications. Immediately after reconstruction, the airway diameter returned to the prestenotic diameter and was maintained till the end of this study 6 weeks postoperatively as measured by endotracheal tube sizing. Histological examination revealed complete epithelization over all the grafted regions except at small areas with minimal granulations in 4 dogs. Viable grafts were identified in 8 cases and 3 cases with insignificant necrosis. This study suggests that rigid distraction of the stenotic airway with microplates and auricular cartilage graft has a good surgical outcome. Allowing repair of the stenosis without stenting or tracheostomy and provides immediate airway stability.ConclusionIn conclusion, the technique of using external fixation with microplates to provide immediate rigid external support and auricular cartilage graft promise to be very helpful in maintaining distraction of the divided anterior cricoid and upper tracheal segments obviating the need for tracheostomy or prolonged stenting.The auricular cartilage is a useful grafting material for LTR because it closely resembles the strength and width of the tracheal cartilage and can be used effectively for a grade I or II stenosis. It has the advantage of having minimal donor site morbidity the auricular cartilage graft-in laryngotracheal reconstruction is more successful than the anterior cricoid split operation treating mild to moderate SGS we have had limited success with ACGs in grade III stenosis and are reluctant to use them in grade IV stenosis, staged reconstruction long-segment SGS, long-segment tracheal stenosis, or revision of a failed auricular or costal cartilage LTR.Summary and ConclusionIn laryngeal expansion surgery for subglottic and tracheal stenosis, after vertically dividing the stenotic segment in the midline and insertion of graft material between the divided segments, either prolonged stenting with tracheostomy (4-6 weeks) or short-term stenting using endotracheal tube with sedation or mechanical ventilation (1-2 weeks) is required until the airway is stabilized. The postoperative period is far more difficult and requires meticulous skillful care. This experimental study was designed to explore the use of microplates and auricular cartilage graft in providing immediate airway stability and to determine the surgical outcome of this procedure. Subglottic stenosis was ceriated in 11 dogs using repeated abrasive technique to the mucosa and perichondrium. All 11 dogs underwent laryngotracheal reconstruction without intraoperative complications. Immediately after reconstruction, the airway diameter returned to the prestenotic diameter and was maintained till the end of this study 6 weeks postoperatively as measured by endotracheal tube sizing. Histological examination revealed complete epithelization over all the grafted regions except at small areas with minimal granulations in 4 dogs. Viable grafts were identified in 8 cases and 3 cases with insignificant necrosis. This study suggests that rigid distraction of the stenotic airway with microplates and auricular cartilage graft has a good surgical outcome. Allowing repair of the stenosis without stenting or tracheostomy and provides immediate airway stability.ConclusionIn conclusion, the technique of using external fixation with microplates to provide immediate rigid external support and auricular cartilage graft promise to be very helpful in maintaining distraction of the divided anterior cricoid and upper tracheal segments obviating the need for tracheostomy or prolonged stenting.The auricular cartilage is a useful grafting material for LTR because it closely resembles the strength and width of the tracheal cartilage and can be used effectively for a grade I or II stenosis. It has the advantage of having minimal donor site morbidity the auricular cartilage graft-in laryngotracheal reconstruction is more successful than the anterior cricoid split operation treating mild to moderate SGS we have had limited success with ACGs in grade III stenosis and are reluctant to use them in grade IV stenosis, staged reconstruction long-segment SGS, long-segment tracheal stenosis, or revision of a failed auricular or costal cartilage LTR.Summary and ConclusionIn laryngeal expansion surgery for subglottic and tracheal stenosis, after vertically dividing the stenotic segment in the midline and insertion of graft material between the divided segments, either prolonged stenting with tracheostomy (4-6 weeks) or short-term stenting using endotracheal tube with sedation or mechanical ventilation (1-2 weeks) is required until the airway is stabilized. The postoperative period is far more difficult and requires meticulous skillful care. This experimental study was designed to explore the use of microplates and auricular cartilage graft in providing immediate airway stability and to determine the surgical outcome of this procedure. Subglottic stenosis was ceriated in 11 dogs using repeated abrasive technique to the mucosa and perichondrium. All 11 dogs underwent laryngotracheal reconstruction without intraoperative complications. Immediately after reconstruction, the airway diameter returned to the prestenotic diameter and was maintained till the end of this study 6 weeks postoperatively as measured by endotracheal tube sizing. Histological examination revealed complete epithelization over all the grafted regions except at small areas with minimal granulations in 4 dogs. Viable grafts were identified in 8 cases and 3 cases with insignificant necrosis. This study suggests that rigid distraction of the stenotic airway with microplates and auricular cartilage graft has a good surgical outcome. Allowing repair of the stenosis without stenting or tracheostomy and provides immediate airway stability.ConclusionIn conclusion, the technique of using external fixation with microplates to provide immediate rigid external support and auricular cartilage graft promise to be very helpful in maintaining distraction of the divided anterior cricoid and upper tracheal segments obviating the need for tracheostomy or prolonged stenting.The auricular cartilage is a useful grafting material for LTR because it closely resembles the strength and width of the tracheal cartilage and can be used effectively for a grade I or II stenosis. It has the advantage of having minimal donor site morbidity the auricular cartilage graft-in laryngotracheal reconstruction is more successful than the anterior cricoid split operation treating mild to moderate SGS we have had limited success with ACGs in grade III stenosis and are reluctant to use them in grade IV stenosis, staged reconstruction long-segment SGS, long-segment tracheal stenosis, or revision of a failed auricular or costal cartilage LTR.Summary and ConclusionIn laryngeal expansion surgery for subglottic and tracheal stenosis, after vertically dividing the stenotic segment in the midline and insertion of graft material between the divided segments, either prolonged stenting with tracheostomy (4-6 weeks) or short-term stenting using endotracheal tube with sedation or mechanical ventilation (1-2 weeks) is required until the airway is stabilized. The postoperative period is far more difficult and requires meticulous skillful care. This experimental study was designed to explore the use of microplates and auricular cartilage graft in providing immediate airway stability and to determine the surgical outcome of this procedure. Subglottic stenosis was ceriated in 11 dogs using repeated abrasive technique to the mucosa and perichondrium. All 11 dogs underwent laryngotracheal reconstruction without intraoperative complications. Immediately after reconstruction, the airway diameter returned to the prestenotic diameter and was maintained till the end of this study 6 weeks postoperatively as measured by endotracheal tube sizing. Histological examination revealed complete epithelization over all the grafted regions except at small areas with minimal granulations in 4 dogs. Viable grafts were identified in 8 cases and 3 cases with insignificant necrosis. This study suggests that rigid distraction of the stenotic airway with microplates and auricular cartilage graft has a good surgical outcome. Allowing repair of the stenosis without stenting or tracheostomy and provides immediate airway stability.ConclusionIn conclusion, the technique of using external fixation with microplates to provide immediate rigid external support and auricular cartilage graft promise to be very helpful in maintaining distraction of the divided anterior cricoid and upper tracheal segments obviating the need for tracheostomy or prolonged stenting.The auricular cartilage is a useful grafting material for LTR because it closely resembles the strength and width of the tracheal cartilage and can be used effectively for a grade I or II stenosis. It has the advantage of having minimal donor site morbidity the auricular cartilage graft-in laryngotracheal reconstruction is more successful than the anterior cricoid split operation treating mild to moderate SGS we have had limited success with ACGs in grade III stenosis and are reluctant to use them in grade IV stenosis, staged reconstruction long-segment SGS, long-segment tracheal stenosis, or revision of a failed auricular or costal cartilage LTR.Summary and ConclusionIn laryngeal expansion surgery for subglottic and tracheal stenosis, after vertically dividing the stenotic segment in the midline and insertion of graft material between the divided segments, either prolonged stenting with tracheostomy (4-6 weeks) or short-term stenting using endotracheal tube with sedation or mechanical ventilation (1-2 weeks) is required until the airway is stabilized. The postoperative period is far more difficult and requires meticulous skillful care. This experimental study was designed to explore the use of microplates and auricular cartilage graft in providing immediate airway stability and to determine the surgical outcome of this procedure. Subglottic stenosis was ceriated in 11 dogs using repeated abrasive technique to the mucosa and perichondrium. All 11 dogs underwent laryngotracheal reconstruction without intraoperative complications. Immediately after reconstruction, the airway diameter returned to the prestenotic diameter and was maintained till the end of this study 6 weeks postoperatively as measured by endotracheal tube sizing. Histological examination revealed complete epithelization over all the grafted regions except at small areas with minimal granulations in 4 dogs. Viable grafts were identified in 8 cases and 3 cases with insignificant necrosis. This study suggests that rigid distraction of the stenotic airway with microplates and auricular cartilage graft has a good surgical outcome. Allowing repair of the stenosis without stenting or tracheostomy and provides immediate airway stability.ConclusionIn conclusion, the technique of using external fixation with microplates to provide immediate rigid external support and auricular cartilage graft promise to be very helpful in maintaining distraction of the divided anterior cricoid and upper tracheal segments obviating the need for tracheostomy or prolonged stenting.The auricular cartilage is a useful grafting material for LTR because it closely resembles the strength and width of the tracheal cartilage and can be used effectively for a grade I or II stenosis. It has the advantage of having minimal donor site morbidity the auricular cartilage graft-in laryngotracheal reconstruction is more successful than the anterior cricoid split operation treating mild to moderate SGS we have had limited success with ACGs in grade III stenosis and are reluctant to use them in grade IV stenosis, staged reconstruction long-segment SGS, long-segment tracheal stenosis, or revision of a failed auricular or costal cartilage LTR.Summary and ConclusionIn laryngeal expansion surgery for subglottic and tracheal stenosis, after vertically dividing the stenotic segment in the midline and insertion of graft material between the divided segments, either prolonged stenting with tracheostomy (4-6 weeks) or short-term stenting using endotracheal tube with sedation or mechanical ventilation (1-2 weeks) is required until the airway is stabilized. The postoperative period is far more difficult and requires meticulous skillful care. This experimental study was designed to explore the use of microplates and auricular cartilage graft in providing immediate airway stability and to determine the surgical outcome of this procedure. Subglottic stenosis was ceriated in 11 dogs using repeated abrasive technique to the mucosa and perichondrium. All 11 dogs underwent laryngotracheal reconstruction without intraoperative complications. Immediately after reconstruction, the airway diameter returned to the prestenotic diameter and was maintained till the end of this study 6 weeks postoperatively as measured by endotracheal tube sizing. Histological examination revealed complete epithelization over all the grafted regions except at small areas with minimal granulations in 4 dogs. Viable grafts were identified in 8 cases and 3 cases with insignificant necrosis. This study suggests that rigid distraction of the stenotic airway with microplates and auricular cartilage graft has a good surgical outcome. Allowing repair of the stenosis without stenting or tracheostomy and provides immediate airway stability.ConclusionIn conclusion, the technique of using external fixation with microplates to provide immediate rigid external support and auricular cartilage graft promise to be very helpful in maintaining distraction of the divided anterior cricoid and upper tracheal segments obviating the need for tracheostomy or prolonged stenting.The auricular cartilage is a useful grafting material for LTR because it closely resembles the strength and width of the tracheal cartilage and can be used effectively for a grade I or II stenosis. It has the advantage of having minimal donor site morbidity the auricular cartilage graft-in laryngotracheal reconstruction is more successful than the anterior cricoid split operation treating mild to moderate SGS we have had limited success with ACGs in grade III stenosis and are reluctant to use them in grade IV stenosis, staged reconstruction long-segment SGS, long-segment tracheal stenosis, or revision of a failed auricular or costal cartilage LTR.Summary and ConclusionIn laryngeal expansion surgery for subglottic and tracheal stenosis, after vertically dividing the stenotic segment in the midline and insertion of graft material between the divided segments, either prolonged stenting with tracheostomy (4-6 weeks) or short-term stenting using endotracheal tube with sedation or mechanical ventilation (1-2 weeks) is required until the airway is stabilized. The postoperative period is far more difficult and requires meticulous skillful care. This experimental study was designed to explore the use of microplates and auricular cartilage graft in providing immediate airway stability and to determine the surgical outcome of this procedure. Subglottic stenosis was ceriated in 11 dogs using repeated abrasive technique to the mucosa and perichondrium. All 11 dogs underwent laryngotracheal reconstruction without intraoperative complications. Immediately after reconstruction, the airway diameter returned to the prestenotic diameter and was maintained till the end of this study 6 weeks postoperatively as measured by endotracheal tube sizing. Histological examination revealed complete epithelization over all the grafted regions except at small areas with minimal granulations in 4 dogs. Viable grafts were identified in 8 cases and 3 cases with insignificant necrosis. This study suggests that rigid distraction of the stenotic airway with microplates and auricular cartilage graft has a good surgical outcome. Allowing repair of the stenosis without stenting or tracheostomy and provides immediate airway stability.ConclusionIn conclusion, the technique of using external fixation with microplates to provide immediate rigid external support and auricular cartilage graft promise to be very helpful in maintaining distraction of the divided anterior cricoid and upper tracheal segments obviating the need for tracheostomy or prolonged stenting.The auricular cartilage is a useful grafting material for LTR because it closely resembles the strength and width of the tracheal cartilage and can be used effectively for a grade I or II stenosis. It has the advantage of having minimal donor site morbidity the auricular cartilage graft-in laryngotracheal reconstruction is more successful than the anterior cricoid split operation treating mild to moderate SGS we have had limited success with ACGs in grade III stenosis and are reluctant to use them in grade IV stenosis, staged reconstruction long-segment SGS, long-segment tracheal stenosis, or revision of a failed auricular or costal cartilage LTR.Summary and ConclusionIn laryngeal expansion surgery for subglottic and tracheal stenosis, after vertically dividing the stenotic segment in the midline and insertion of graft material between the divided segments, either prolonged stenting with tracheostomy (4-6 weeks) or short-term stenting using endotracheal tube with sedation or mechanical ventilation (1-2 weeks) is required until the airway is stabilized. The postoperative period is far more difficult and requires meticulous skillful care. This experimental study was designed to explore the use of microplates and auricular cartilage graft in providing immediate airway stability and to determine the surgical outcome of this procedure. Subglottic stenosis was ceriated in 11 dogs using repeated abrasive technique to the mucosa and perichondrium. All 11 dogs underwent laryngotracheal reconstruction without intraoperative complications. Immediately after reconstruction, the airway diameter returned to the prestenotic diameter and was maintained till the end of this study 6 weeks postoperatively as measured by endotracheal tube sizing. Histological examination revealed complete epithelization over all the grafted regions except at small areas with minimal granulations in 4 dogs. Viable grafts were identified in 8 cases and 3 cases with insignificant necrosis. This study suggests that rigid distraction of the stenotic airway with microplates and auricular cartilage graft has a good surgical outcome. Allowing repair of the stenosis without stenting or tracheostomy and provides immediate airway stability.ConclusionIn conclusion, the technique of using external fixation with microplates to provide immediate rigid external support and auricular cartilage graft promise to be very helpful in maintaining distraction of the divided anterior cricoid and upper tracheal segments obviating the need for tracheostomy or prolonged stenting.The auricular cartilage is a useful grafting material for LTR because it closely resembles the strength and width of the tracheal cartilage and can be used effectively for a grade I or II stenosis. It has the advantage of having minimal donor site morbidity the auricular cartilage graft-in laryngotracheal reconstruction is more successful than the anterior cricoid split operation treating mild to moderate SGS we have had limited success with ACGs in grade III stenosis and are reluctant to use them in grade IV stenosis, staged reconstruction long-segment SGS, long-segment tracheal stenosis, or revision of a failed auricular or costal cartilage LTR.Summary and ConclusionIn laryngeal expansion surgery for subglottic and tracheal stenosis, after vertically dividing the stenotic segment in the midline and insertion of graft material between the divided segments, either prolonged stenting with tracheostomy (4-6 weeks) or short-term stenting using endotracheal tube with sedation or mechanical ventilation (1-2 weeks) is required until the airway is stabilized. The postoperative period is far more difficult and requires meticulous skillful care. This experimental study was designed to explore the use of microplates and auricular cartilage graft in providing immediate airway stability and to determine the surgical outcome of this procedure. Subglottic stenosis was ceriated in 11 dogs using repeated abrasive technique to the mucosa and perichondrium. All 11 dogs underwent laryngotracheal reconstruction without intraoperative complications. Immediately after reconstruction, the airway diameter returned to the prestenotic diameter and was maintained till the end of this study 6 weeks postoperatively as measured by endotracheal tube sizing. Histological examination revealed complete epithelization over all the grafted regions except at small areas with minimal granulations in 4 dogs. Viable grafts were identified in 8 cases and 3 cases with insignificant necrosis. This study suggests that rigid distraction of the stenotic airway with microplates and auricular cartilage graft has a good surgical outcome. Allowing repair of the stenosis without stenting or tracheostomy and provides immediate airway stability.ConclusionIn conclusion, the technique of using external fixation with microplates to provide immediate rigid external support and auricular cartilage graft promise to be very helpful in maintaining distraction of the divided anterior cricoid and upper tracheal segments obviating the need for tracheostomy or prolonged stenting.The auricular cartilage is a useful grafting material for LTR because it closely resembles the strength and width of the tracheal cartilage and can be used effectively for a grade I or II stenosis. It has the advantage of having minimal donor site morbidity the auricular cartilage graft-in laryngotracheal reconstruction is more successful than the anterior cricoid split operation treating mild to moderate SGS we have had limited success with ACGs in grade III stenosis and are reluctant to use them in grade IV stenosis, staged reconstruction long-segment SGS, long-segment tracheal stenosis, or revision of a failed auricular or costal cartilage LTR.Summary and ConclusionIn laryngeal expansion surgery for subglottic and tracheal stenosis, after vertically dividing the stenotic segment in the midline and insertion of graft material between the divided segments, either prolonged stenting with tracheostomy (4-6 weeks) or short-term stenting using endotracheal tube with sedation or mechanical ventilation (1-2 weeks) is required until the airway is stabilized. The postoperative period is far more difficult and requires meticulous skillful care. This experimental study was designed to explore the use of microplates and auricular cartilage graft in providing immediate airway stability and to determine the surgical outcome of this procedure. Subglottic stenosis was ceriated in 11 dogs using repeated abrasive technique to the mucosa and perichondrium. All 11 dogs underwent laryngotracheal reconstruction without intraoperative complications. Immediately after reconstruction, the airway diameter returned to the prestenotic diameter and was maintained till the end of this study 6 weeks postoperatively as measured by endotracheal tube sizing. Histological examination revealed complete epithelization over all the grafted regions except at small areas with minimal granulations in 4 dogs. Viable grafts were identified in 8 cases and 3 cases with insignificant necrosis. This study suggests that rigid distraction of the stenotic airway with microplates and auricular cartilage graft has a good surgical outcome. Allowing repair of the stenosis without stenting or tracheostomy and provides immediate airway stability.ConclusionIn conclusion, the technique of using external fixation with microplates to provide immediate rigid external support and auricular cartilage graft promise to be very helpful in maintaining distraction of the divided anterior cricoid and upper tracheal segments obviating the need for tracheostomy or prolonged stenting.The auricular cartilage is a useful grafting material for LTR because it closely resembles the strength and width of the tracheal cartilage and can be used effectively for a grade I or II stenosis. It has the advantage of having minimal donor site morbidity the auricular cartilage graft-in laryngotracheal reconstruction is more successful than the anterior cricoid split operation treating mild to moderate SGS we have had limited success with ACGs in grade III stenosis and are reluctant to use them in grade IV stenosis, staged reconstruction long-segment SGS, long-segment tracheal stenosis, or revision of a failed auricular or costal cartilage LTR.Summary and ConclusionIn laryngeal expansion surgery for subglottic and tracheal stenosis, after vertically dividing the stenotic segment in the midline and insertion of graft material between the divided segments, either prolonged stenting with tracheostomy (4-6 weeks) or short-term stenting using endotracheal tube with sedation or mechanical ventilation (1-2 weeks) is required until the airway is stabilized. The postoperative period is far more difficult and requires meticulous skillful care. This experimental study was designed to explore the use of microplates and auricular cartilage graft in providing immediate airway stability and to determine the surgical outcome of this procedure. Subglottic stenosis was ceriated in 11 dogs using repeated abrasive technique to the mucosa and perichondrium. All 11 dogs underwent laryngotracheal reconstruction without intraoperative complications. Immediately after reconstruction, the airway diameter returned to the prestenotic diameter and was maintained till the end of this study 6 weeks postoperatively as measured by endotracheal tube sizing. Histological examination revealed complete epithelization over all the grafted regions except at small areas with minimal granulations in 4 dogs. Viable grafts were identified in 8 cases and 3 cases with insignificant necrosis. This study suggests that rigid distraction of the stenotic airway with microplates and auricular cartilage graft has a good surgical outcome. Allowing repair of the stenosis without stenting or tracheostomy and provides immediate airway stability.ConclusionIn conclusion, the technique of using external fixation with microplates to provide immediate rigid external support and auricular cartilage graft promise to be very helpful in maintaining distraction of the divided anterior cricoid and upper tracheal segments obviating the need for tracheostomy or prolonged stenting.The auricular cartilage is a useful grafting material for LTR because it closely resembles the strength and width of the tracheal cartilage and can be used effectively for a grade I or II stenosis. It has the advantage of having minimal donor site morbidity the auricular cartilage graft-in laryngotracheal reconstruction is more successful than the anterior cricoid split operation treating mild to moderate SGS we have had limited success with ACGs in grade III stenosis and are reluctant to use them in grade IV stenosis, staged reconstruction long-segment SGS, long-segment tracheal stenosis, or revision of a failed auricular or costal cartilage LTR.Summary and ConclusionIn laryngeal expansion surgery for subglottic and tracheal stenosis, after vertically dividing the stenotic segment in the midline and insertion of graft material between the divided segments, either prolonged stenting with tracheostomy (4-6 weeks) or short-term stenting using endotracheal tube with sedation or mechanical ventilation (1-2 weeks) is required until the airway is stabilized. The postoperative period is far more difficult and requires meticulous skillful care. This experimental study was designed to explore the use of microplates and auricular cartilage graft in providing immediate airway stability and to determine the surgical outcome of this procedure. Subglottic stenosis was ceriated in 11 dogs using repeated abrasive technique to the mucosa and perichondrium. All 11 dogs underwent laryngotracheal reconstruction without intraoperative complications. Immediately after reconstruction, the airway diameter returned to the prestenotic diameter and was maintained till the end of this study 6 weeks postoperatively as measured by endotracheal tube sizing. Histological examination revealed complete epithelization over all the grafted regions except at small areas with minimal granulations in 4 dogs. Viable grafts were identified in 8 cases and 3 cases with insignificant necrosis. This study suggests that rigid distraction of the stenotic airway with microplates and auricular cartilage graft has a good surgical outcome. Allowing repair of the stenosis without stenting or tracheostomy and provides immediate airway stability.ConclusionIn conclusion, the technique of using external fixation with microplates to provide immediate rigid external support and auricular cartilage graft promise to be very helpful in maintaining distraction of the divided anterior cricoid and upper tracheal segments obviating the need for tracheostomy or prolonged stenting.The auricular cartilage is a useful grafting material for LTR because it closely resembles the strength and width of the tracheal cartilage and can be used effectively for a grade I or II stenosis. It has the advantage of having minimal donor site morbidity the auricular cartilage graft-in laryngotracheal reconstruction is more successful than the anterior cricoid split operation treating mild to moderate SGS we have had limited success with ACGs in grade III stenosis and are reluctant to use them in grade IV stenosis, staged reconstruction long-segment SGS, long-segment tracheal stenosis, or revision of a failed auricular or costal cartilage LTR.Summary and ConclusionIn laryngeal expansion surgery for subglottic and tracheal stenosis, after vertically dividing the stenotic segment in the midline and insertion of graft material between the divided segments, either prolonged stenting with tracheostomy (4-6 weeks) or short-term stenting using endotracheal tube with sedation or mechanical ventilation (1-2 weeks) is required until the airway is stabilized. The postoperative period is far more difficult and requires meticulous skillful care. This experimental study was designed to explore the use of microplates and auricular cartilage graft in providing immediate airway stability and to determine the surgical outcome of this procedure. Subglottic stenosis was ceriated in 11 dogs using repeated abrasive technique to the mucosa and perichondrium. All 11 dogs underwent laryngotracheal reconstruction without intraoperative complications. Immediately after reconstruction, the airway diameter returned to the prestenotic diameter and was maintained till the end of this study 6 weeks postoperatively as measured by endotracheal tube sizing. Histological examination revealed complete epithelization over all the grafted regions except at small areas with minimal granulations in 4 dogs. Viable grafts were identified in 8 cases and 3 cases with insignificant necrosis. This study suggests that rigid distraction of the stenotic airway with microplates and auricular cartilage graft has a good surgical outcome. Allowing repair of the stenosis without stenting or tracheostomy and provides immediate airway stability.ConclusionIn conclusion, the technique of using external fixation with microplates to provide immediate rigid external support and auricular cartilage graft promise to be very helpful in maintaining distraction of the divided anterior cricoid and upper tracheal segments obviating the need for tracheostomy or prolonged stenting.The auricular cartilage is a useful grafting material for LTR because it closely resembles the strength and width of the tracheal cartilage and can be used effectively for a grade I or II stenosis. It has the advantage of having minimal donor site morbidity the auricular cartilage graft-in laryngotracheal reconstruction is more successful than the anterior cricoid split operation treating mild to moderate SGS we have had limited success with ACGs in grade III stenosis and are reluctant to use them in grade IV stenosis, staged reconstruction long-segment SGS, long-segment tracheal stenosis, or revision of a failed auricular or costal cartilage LTR.
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