Serum immunoglobulin (m, e and d)pattern in recurrent upper respiratory infections

Maintenance of the body’s integrity is the principal function of the immune system. The immune system has evolved mechanisms which destroy invaders of extrinsic origin e.g. viruses, bacteria as well as invaders of intrinsic origin i.e. neoplastic cells. This immune system is made-up of 2 di vislonp., humo r’e.L immunity which is mediated by B. lymphocytes and cellu - lar immunity which is mediated by T-lymphocytes. Upper respiratory tract infections are by far the commonest diseases and the role of immunity in the pathogenesis and recurrence of these diseases contLued to elude the medical researchers for a long period of time. This work was carried out in the departments of E.N. T., Chest and Biochemistry, Pacu’L ty of Medicine, Zagazig University and was devoted to the study of the possible changes in the immunoglobulin patterns and their relevance to the pathogenesis of r-ecur-r-ent upp oz’ respiratory tract infections. .