| Abstract: |
-3The Bralchial Arches And Neck :The construction of jaws and a neck is closely boundThe recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.(Shirasaka et al.,2003). The concept of the hypothalamus playing a role in the regulation of feeding behavior and energy homeostasis was originally based on observations of brain lesions (Oomura, 1980). Lesions of the ventromedial hypothalamus (VMH) produce hyperphagic obesity, whereas lesions of the lateral hypothalamus (LH) induce hypophagia and weight loss, suggesting that satiety and feeding centres existed in the VMH and LH, respectively(Bernardis and Bellinger,Orexins, also named hypocretins, are neuropeptides present in hypothalamic neurons were discovered in 1998 by subtractive cDNA cloning or orphan receptor technologies. Prepro-orexin is enzymatically matured into two peptides, orexin-A and orexin-B which are 33- and 28-amino-acid peptides, respectively. Two cloned orexin receptors OX1R and OX2R are serpentine G-protein- coupled receptors, both of which bind orexins and are coupled to Ca2+ mobilization.(Sakurai et al.,1988)Orexins are neuropeptides present in hypothalamic neurons that project throughout the central nervous system to nuclei involved in the control of feeding, sleep-wakefulness, neuroendocrine homeostasis and autonomic regulation. (Pyron et al.,1998) The interest of investigators in orexins has focused on narcolepsy , since genetic or experimental alterations of the orexin system are associated with this sleep disorder. However, orexins are not restricted to the hypothalamus and together with their receptors they are expressed in peripheral tissues.(Hungs and Mignot, 2001).The expression of orexins and/or orexin receptors in several peripheral rat tissues suggests a more widespread action of orexins at the periphery in Endocrine pancreas testis, kidney, heart, thyroid and lung [Nowak et al.,2000, 75].Further studies indicate more complex array of orexins functions and effects. The orexin signaling pathway thought to participate in a complex cycle of energy homeostasis , including control of food intake motor activity , metabolic rate, heart rate, and blood pressure.(Preti , 2002).insulin is known as a long-term regulator of food intake and energy balance, orexins play an important role in the adipo-insular axis by stimulating insulin and leptin secretions [Jaszberenyi et al.,2001]orexin-A was also effective in stimulating insulin release in vivo(Irahara et al.,2001) and in an in vitro perfusion system (Nowak et al. ,2000). Nevertheless, from these studies, it is not known whether orexin-A increases insulin release by acting directly on the ?-cells or not (Kirchgessner , 2002).Many lines of evidence indicate that close interrelationships occur between body weight homeostasis and adrenal secretory activity , However, Several lines of evidence suggest that orexins influence neuroendocrine homeostasis and modulate hormone secretions in the hypothalamo-pituitary-adrenal axis (HPA) (Viosin et al.,2003).As both the orexinergic system and the HPA axis are activated in stress conditions , so they may interact to regulate energy homeostasis during stress conditions.Orexin containing fibres project widely to the CNS , and orexin receptors have been found in areas known to participate in the control of the autonomic nervous system(Preti,(2002).Also, Very recent reports indicate that (i) orexin-containing neurons of the lateral hypothalamus project to brown adipose tissue [Nakamura et al.,2000] .Hypocretinergic neurons may regulate sympathetic and cardiovascular activity. Furthermore, their antagonists may apply for the treatment of hypertension and cardiovascular diseases in the future.Further stdies are needed to better understand the signal transduction pathways of orexin receptors; (iv) to evaluate the involvement of orexins in other peripheral functions; (v) to understand the physiological role, if any, of circulating orexin and its site(s) oforigin, i. e. gastrointestinal tract or other sources, and (vi to explore peripheral tissue functions in orexin or orexin receptor knock out mice. Following such studies, orexins will likely be promoted as major regulatory peptides.
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