Infrared, Raman, thermal, kinetic modeling studies of mercury (II) ephedrine complex

The reaction between ephedrine HCl and HgCl2 in 1:2 molar ratio in methanol was investigated at 70 degrees C. In normal conditions, the mercury(II) complex formulated as {[}Hg(eph)(2)](Cl)(2)center dot 2HCl, was formed by chelating of mercuric chloride and ephedrine hydrochloride without pH adjustment. This complex was characterized by elemental analysis, infrared and Raman spectroscopy. IR spectrum of mercury complex show that ephedrine nucleus has two powerful donating sites -OH and -NH groups, so it is prefer to acts as bidentate ligand. The thermal stability mechanism of this complex was carried out by thermo gravimetric (TG) and differential thermo gravimetric (DTG) analysis which is facilitate to recognized the formation of this complex. The Coats-Redfern and Horowitz-Metzger relations were carried out to calculate the thermodynamic parameters. The bond angles, bond lengths, highest occupied molecular orbital (HOMO), the energy of the lowest unoccupied molecular orbital (LUMO) and energy gap of the studied complex were calculated using HyperChem software program. {[}Soha F. Mohammed, Abdel Majid A. Adam and Moamen S. Refat. Infrared, Raman, thermal, kinetic modeling studies of mercury (II) ephedrine complex. Life Sci J. 2012; 9(3): 1332-1342] (ISSN: 1097-8135). http://www.lifesciencesite.com. 192