Summary and ConclusionThis work has been done in the nephrology and dialysis unit, internal medicine department, Zagazig university hospitals.This study included a total number of 25 patients were divided according to site of A-V fistula into two groups;Group I: included 15 patients; 3 of them were females, 12 of them males. Group II: included 10 patients; 4 of them were females and 6 of them were males. Subdivided according to the duration of haemodialysis (dialytic age) into three groups; Group 1 included 5 patients all of them were males, Group 2 included 14 patients 5 of them were females, 9 of them were males, Group 3 included 6 patients 2 of them were females, and 4 of them were males.And also subdivided according to the age of patients into four groups; Group A included 7 patients: (3 of them were female, 4 of them were male) with age ranged 21 - 30 years. Group B included 5 patients (all of them were male), with age ranged 31- 40 years. Group C included 8 patients (1 of them was female, and 7 of them were males) with age ranged 41 - 50 years. Group D included 5 patients (3 of them were female and 2 of them were male) with age ranged 51 - 60 yearsMethods:All patients were subjected to the following:1- Thorough history and Full Clinical Examination.2- Thorough history and Clinical Examination of A-V fistula.3- Haemodialysis program.4- Blood pressure pre- and post dialysis was measured.5- Intradialytic body weight gain.6- Routine investigation (to verify the inclusion and the exclusion criteria of our subjects included:a- Complete blood picture.b- Total protein and serum albumin.c- Liver function test.d- Serum Creatinine blood urea level Pre and post dialysis.e- ECG and Echocardiogram.f- Fasting and post prandial blood sugar to exclude DM.g- Calcium (Ca), Phosphorus (P), Sodium (Na), and Potassium (K).Research investigations included:a- Color Wave Doppler Ultrasound for A-V fistula.b- Prescribed dose of Haemodialysis from Kt/v equation.Our result as following:- The mean Kt/v in female was highly significant higher than in male.- The intra access MBFV in male A-V fistula was significant higher than in female.- The intra access MBFV in arm A-V fistula was highly significant higher than in forearm A-V fistula.- The difference among Kt/v and intra access MBFV as regards the age of patients and duration of haemodialysis (dialytic age) was non-significant.- The difference between Kt/v and intra access MBFV in complicated and uncomplicated A-V fistulae was non-significant.- The difference between Kt/v and intra access MBFV in private and university hospitals constructed A-V fistulae was non-significant.- The mean values of Kt/v was highly significant higher in UKM (Watson and nomogram) than in Daugirdas II.UKM method for Kt/v estimation more specific and more sensitive than in Daugirdas II.Conclusions:From the previous results it could be concluded that:- The intra–access blood flow rate was highly significant higher in arm A-V fistula than in fore arm A-V fistula.- The intra–access blood flow rate was significantly higher in male than in female A-V fistula.- Kt/v in female was highly significant higher than in male.Recommendation- We recommend to estimate the Kt/v by UKM (Watson and Nomogram) at least every month:- Regular examination of A-V fistula every 4 – 6 weeks and do Color Doppler if needed.- Construction of A-V fistula in arm if no contra indication.- The recommended ideal intra-access blood flow rate need further study on a wider scale.Summary and ConclusionThis work has been done in the nephrology and dialysis unit, internal medicine department, Zagazig university hospitals.This study included a total number of 25 patients were divided according to site of A-V fistula into two groups;Group I: included 15 patients; 3 of them were females, 12 of them males. Group II: included 10 patients; 4 of them were females and 6 of them were males. Subdivided according to the duration of haemodialysis (dialytic age) into three groups; Group 1 included 5 patients all of them were males, Group 2 included 14 patients 5 of them were females, 9 of them were males, Group 3 included 6 patients 2 of them were females, and 4 of them were males.And also subdivided according to the age of patients into four groups; Group A included 7 patients: (3 of them were female, 4 of them were male) with age ranged 21 - 30 years. Group B included 5 patients (all of them were male), with age ranged 31- 40 years. Group C included 8 patients (1 of them was female, and 7 of them were males) with age ranged 41 - 50 years. Group D included 5 patients (3 of them were female and 2 of them were male) with age ranged 51 - 60 yearsMethods:All patients were subjected to the following:1- Thorough history and Full Clinical Examination.2- Thorough history and Clinical Examination of A-V fistula.3- Haemodialysis program.4- Blood pressure pre- and post dialysis was measured.5- Intradialytic body weight gain.6- Routine investigation (to verify the inclusion and the exclusion criteria of our subjects included:a- Complete blood picture.b- Total protein and serum albumin.c- Liver function test.d- Serum Creatinine blood urea level Pre and post dialysis.e- ECG and Echocardiogram.f- Fasting and post prandial blood sugar to exclude DM.g- Calcium (Ca), Phosphorus (P), Sodium (Na), and Potassium (K).Research investigations included:a- Color Wave Doppler Ultrasound for A-V fistula.b- Prescribed dose of Haemodialysis from Kt/v equation.Our result as following:- The mean Kt/v in female was highly significant higher than in male.- The intra access MBFV in male A-V fistula was significant higher than in female.- The intra access MBFV in arm A-V fistula was highly significant higher than in forearm A-V fistula.- The difference among Kt/v and intra access MBFV as regards the age of patients and duration of haemodialysis (dialytic age) was non-significant.- The difference between Kt/v and intra access MBFV in complicated and uncomplicated A-V fistulae was non-significant.- The difference between Kt/v and intra access MBFV in private and university hospitals constructed A-V fistulae was non-significant.- The mean values of Kt/v was highly significant higher in UKM (Watson and nomogram) than in Daugirdas II.UKM method for Kt/v estimation more specific and more sensitive than in Daugirdas II.Conclusions:From the previous results it could be concluded that:- The intra–access blood flow rate was highly significant higher in arm A-V fistula than in fore arm A-V fistula.- The intra–access blood flow rate was significantly higher in male than in female A-V fistula.- Kt/v in female was highly significant higher than in male.Recommendation- We recommend to estimate the Kt/v by UKM (Watson and Nomogram) at least every month:- Regular examination of A-V fistula every 4 – 6 weeks and do Color Doppler if needed.- Construction of A-V fistula in arm if no contra indication.- The recommended ideal intra-access blood flow rate need further study on a wider scale.Summary and ConclusionThis work has been done in the nephrology and dialysis unit, internal medicine department, Zagazig university hospitals.This study included a total number of 25 patients were divided according to site of A-V fistula into two groups;Group I: included 15 patients; 3 of them were females, 12 of them males. Group II: included 10 patients; 4 of them were females and 6 of them were males. Subdivided according to the duration of haemodialysis (dialytic age) into three groups; Group 1 included 5 patients all of them were males, Group 2 included 14 patients 5 of them were females, 9 of them were males, Group 3 included 6 patients 2 of them were females, and 4 of them were males.And also subdivided according to the age of patients into four groups; Group A included 7 patients: (3 of them were female, 4 of them were male) with age ranged 21 - 30 years. Group B included 5 patients (all of them were male), with age ranged 31- 40 years. Group C included 8 patients (1 of them was female, and 7 of them were males) with age ranged 41 - 50 years. Group D included 5 patients (3 of them were female and 2 of them were male) with age ranged 51 - 60 yearsMethods:All patients were subjected to the following:1- Thorough history and Full Clinical Examination.2- Thorough history and Clinical Examination of A-V fistula.3- Haemodialysis program.4- Blood pressure pre- and post dialysis was measured.5- Intradialytic body weight gain.6- Routine investigation (to verify the inclusion and the exclusion criteria of our subjects included:a- Complete blood picture.b- Total protein and serum albumin.c- Liver function test.d- Serum Creatinine blood urea level Pre and post dialysis.e- ECG and Echocardiogram.f- Fasting and post prandial blood sugar to exclude DM.g- Calcium (Ca), Phosphorus (P), Sodium (Na), and Potassium (K).Research investigations included:a- Color Wave Doppler Ultrasound for A-V fistula.b- Prescribed dose of Haemodialysis from Kt/v equation.Our result as following:- The mean Kt/v in female was highly significant higher than in male.- The intra access MBFV in male A-V fistula was significant higher than in female.- The intra access MBFV in arm A-V fistula was highly significant higher than in forearm A-V fistula.- The difference among Kt/v and intra access MBFV as regards the age of patients and duration of haemodialysis (dialytic age) was non-significant.- The difference between Kt/v and intra access MBFV in complicated and uncomplicated A-V fistulae was non-significant.- The difference between Kt/v and intra access MBFV in private and university hospitals constructed A-V fistulae was non-significant.- The mean values of Kt/v was highly significant higher in UKM (Watson and nomogram) than in Daugirdas II.UKM method for Kt/v estimation more specific and more sensitive than in Daugirdas II.Conclusions:From the previous results it could be concluded that:- The intra–access blood flow rate was highly significant higher in arm A-V fistula than in fore arm A-V fistula.- The intra–access blood flow rate was significantly higher in male than in female A-V fistula.- Kt/v in female was highly significant higher than in male.Recommendation- We recommend to estimate the Kt/v by UKM (Watson and Nomogram) at least every month:- Regular examination of A-V fistula every 4 – 6 weeks and do Color Doppler if needed.- Construction of A-V fistula in arm if no contra indication.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.The lesions encountered in our study were classified into 22 malignant lesions and 8 of benign nature.The malignant lesions were further subdivided into tumors arised from the nasopharynx itself, they were squamous cell carcinoma in 12 patients, lymphoma in 8 patients, and malignant tumors extended to the nasopharynx in the form of chordoma and carcinoma of the maxillary sinus.Eight patients with benign lesions were included in our series, further subdivided into 6 cases arised from the nasopharynx, they were 3 cases of angiofibroma, 3 cases of adenoids, or direct extension from adjacent structures in two cases, one case of nasal angiofibroma and the other was pleomorphic adenoma of the deep part of the parotid gland.Both CT and MRI were done for all our patients, CT was effective in the determination of the lesion, extension, other close association, the bone destruction and abnormal calcifications inside the tumor, however CT failed to distinguish between the tumor itself and the surrounding soft tissue structures.MRI is a sensitive technique in good differentiation between the tumor itself and the surrounding structures, the extension and the obliteration of the surrounding spaces, MRI has also good advantages of determination of the intracranial extension.In conclusion:The Computed Tomography is effective in imaging of the nasopharyngeal lesions as if they are primarily arise from or as an extension from the parapharyngeal structures. It also provides a good details about the nature of the lesion, density, extension and other association and presence of calcifications or bone destruction, which is deficient in MR imaging.The advantages of MR imaging with its superior soft tissue contrast resolution, absence of bone hardening artifacts, and ability to image in multiplanner fashion has allowed to image the deep fascial structures as well as the distinction between the tumor and the surrounding soft tissue is easier than that of computed tomography.So both CT and MRI are well-established methods in diagnosing diseases of the nasopharynx and its surrounding.The recommended diagnostic strategy for mass lesions of the nasopharynx and surrounding structures is to use Gd-enhanced MRI as a primary study and contrast enhanced CT as a secondary study for the evaluation of fine bony details.Summary and conclusionThe aim of this study is to assess the accuracy of magnetic resonance imaging versus computed tomography in diagnosis of nasopharyngeal mass.This study was done during the period from June 2002 to December 2003 in Radiology Departments, Zagazig University Hospitals. The study included 30 patients, 19 males and 11 females, their ages ranged from 5 to 69 years.The patients were subjected to:1- Clinical examination.2- CT scanning.3- MRI4- Histopathological analysis.- The recommended ideal intra-access blood flow rate need further study on a wider scale.Summary and ConclusionThis work has been done in the nephrology and dialysis unit, internal medicine department, Zagazig university hospitals.This study included a total number of 25 patients were divided according to site of A-V fistula into two groups;Group I: included 15 patients; 3 of them were females, 12 of them males. Group II: included 10 patients; 4 of them were females and 6 of them were males. Subdivided according to the duration of haemodialysis (dialytic age) into three groups; Group 1 included 5 patients all of them were males, Group 2 included 14 patients 5 of them were females, 9 of them were males, Group 3 included 6 patients 2 of them were females, and 4 of them were males.And also subdivided according to the age of patients into four groups; Group A included 7 patients: (3 of them were female, 4 of them were male) with age ranged 21 - 30 years. Group B included 5 patients (all of them were male), with age ranged 31- 40 years. Group C included 8 patients (1 of them was female, and 7 of them were males) with age ranged 41 - 50 years. Group D included 5 patients (3 of them were female and 2 of them were male) with age ranged 51 - 60 yearsMethods:All patients were subjected to the following:1- Thorough history and Full Clinical Examination.2- Thorough history and Clinical Examination of A-V fistula.3- Haemodialysis program.4- Blood pressure pre- and post dialysis was measured.5- Intradialytic body weight gain.6- Routine investigation (to verify the inclusion and the exclusion criteria of our subjects included:a- Complete blood picture.b- Total protein and serum albumin.c- Liver function test.d- Serum Creatinine blood urea level Pre and post dialysis.e- ECG and Echocardiogram.f- Fasting and post prandial blood sugar to exclude DM.g- Calcium (Ca), Phosphorus (P), Sodium (Na), and Potassium (K).Research investigations included:a- Color Wave Doppler Ultrasound for A-V fistula.b- Prescribed dose of Haemodialysis from Kt/v equation.Our result as following:- The mean Kt/v in female was highly significant higher than in male.- The intra access MBFV in male A-V fistula was significant higher than in female.- The intra access MBFV in arm A-V fistula was highly significant higher than in forearm A-V fistula.- The difference among Kt/v and intra access MBFV as regards the age of patients and duration of haemodialysis (dialytic age) was non-significant.- The difference between Kt/v and intra access MBFV in complicated and uncomplicated A-V fistulae was non-significant.- The difference between Kt/v and intra access MBFV in private and university hospitals constructed A-V fistulae was non-significant.- The mean values of Kt/v was highly significant higher in UKM (Watson and nomogram) than in Daugirdas II.UKM method for Kt/v estimation more specific and more sensitive than in Daugirdas II.Conclusions:From the previous results it could be concluded that:- The intra–access blood flow rate was highly significant higher in arm A-V fistula than in fore arm A-V fistula.- The intra–access blood flow rate was significantly higher in male than in female A-V fistula.- Kt/v in female was highly significant higher than in male.Recommendation- We recommend to estimate the Kt/v by UKM (Watson and Nomogram) at least every month:- Regular examination of A-V fistula every 4 – 6 weeks and do Color Doppler if needed.- Construction of A-V fistula in arm if no contra indication.- The recommended ideal intra-access blood flow rate need further study on a wider scale.Summary and ConclusionThis work has been done in the nephrology and dialysis unit, internal medicine department, Zagazig university hospitals.This study included a total number of 25 patients were divided according to site of A-V fistula into two groups;Group I: included 15 patients; 3 of them were females, 12 of them males. Group II: included 10 patients; 4 of them were females and 6 of them were males. Subdivided according to the duration of haemodialysis (dialytic age) into three groups; Group 1 included 5 patients all of them were males, Group 2 included 14 patients 5 of them were females, 9 of them were males, Group 3 included 6 patients 2 of them were females, and 4 of them were males.And also subdivided according to the age of patients into four groups; Group A included 7 patients: (3 of them were female, 4 of them were male) with age ranged 21 - 30 years. Group B included 5 patients (all of them were male), with age ranged 31- 40 years. Group C included 8 patients (1 of them was female, and 7 of them were males) with age ranged 41 - 50 years. Group D included 5 patients (3 of them were female and 2 of them were male) with age ranged 51 - 60 yearsMethods:All patients were subjected to the following:1- Thorough history and Full Clinical Examination.2- Thorough history and Clinical Examination of A-V fistula.3- Haemodialysis program.4- Blood pressure pre- and post dialysis was measured.5- Intradialytic body weight gain.6- Routine investigation (to verify the inclusion and the exclusion criteria of our subjects included:a- Complete blood picture.b- Total protein and serum albumin.c- Liver function test.d- Serum Creatinine blood urea level Pre and post dialysis.e- ECG and Echocardiogram.f- Fasting and post prandial blood sugar to exclude DM.g- Calcium (Ca), Phosphorus (P), Sodium (Na), and Potassium (K).Research investigations included:a- Color Wave Doppler Ultrasound for A-V fistula.b- Prescribed dose of Haemodialysis from Kt/v equation.Our result as following:- The mean Kt/v in female was highly significant higher than in male.- The intra access MBFV in male A-V fistula was significant higher than in female.- The intra access MBFV in arm A-V fistula was highly significant higher than in forearm A-V fistula.- The difference among Kt/v and intra access MBFV as regards the age of patients and duration of haemodialysis (dialytic age) was non-significant.- The difference between Kt/v and intra access MBFV in complicated and uncomplicated A-V fistulae was non-significant.- The difference between Kt/v and intra access MBFV in private and university hospitals constructed A-V fistulae was non-significant.- The mean values of Kt/v was highly significant higher in UKM (Watson and nomogram) than in Daugirdas II.UKM method for Kt/v estimation more specific and more sensitive than in Daugirdas II.Conclusions:From the previous results it could be concluded that:- The intra–access blood flow rate was highly significant higher in arm A-V fistula than in fore arm A-V fistula.- The intra–access blood flow rate was significantly higher in male than in female A-V fistula.- Kt/v in female was highly significant higher than in male.Recommendation- We recommend to estimate the Kt/v by UKM (Watson and Nomogram) at least every month:- Regular examination of A-V fistula every 4 – 6 weeks and do Color Doppler if needed.- Construction of A-V fistula in arm if no contra indication.- The recommended ideal intra-access blood flow rate need further study on a wider scale.Summary and ConclusionThis work has been done in the nephrology and dialysis unit, internal medicine department, Zagazig university hospitals.This study included a total number of 25 patients were divided according to site of A-V fistula into two groups;Group I: included 15 patients; 3 of them were females, 12 of them males. Group II: included 10 patients; 4 of them were females and 6 of them were males. Subdivided according to the duration of haemodialysis (dialytic age) into three groups; Group 1 included 5 patients all of them were males, Group 2 included 14 patients 5 of them were females, 9 of them were males, Group 3 included 6 patients 2 of them were females, and 4 of them were males.And also subdivided according to the age of patients into four groups; Group A included 7 patients: (3 of them were female, 4 of them were male) with age ranged 21 - 30 years. Group B included 5 patients (all of them were male), with age ranged 31- 40 years. Group C included 8 patients (1 of them was female, and 7 of them were males) with age ranged 41 - 50 years. Group D included 5 patients (3 of them were female and 2 of them were male) with age ranged 51 - 60 yearsMethods:All patients were subjected to the following:1- Thorough history and Full Clinical Examination.2- Thorough history and Clinical Examination of A-V fistula.3- Haemodialysis program.4- Blood pressure pre- and post dialysis was measured.5- Intradialytic body weight gain.6- Routine investigation (to verify the inclusion and the exclusion criteria of our subjects included:a- Complete blood picture.b- Total protein and serum albumin.c- Liver function test.d- Serum Creatinine blood urea level Pre and post dialysis.e- ECG and Echocardiogram.f- Fasting and post prandial blood sugar to exclude DM.g- Calcium (Ca), Phosphorus (P), Sodium (Na), and Potassium (K).Research investigations included:a- Color Wave Doppler Ultrasound for A-V fistula.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.3- Future studies are needed to confirm the value of QT dispersion in risk stratification after AMI.SUMMARYThere is growing interest in QT dispersion as a marker for arrhythmia potential being a marker of inhomogenicity of ventricular repolarization. The QT dispersion is increased in myocardial ischemia and infarction, and levels are higher in patients with ventricular arrhythmias. This study was performed to assess QT dispersion in patients with acute myocardial infarction treated with thrombolytic therapy with successful reperfusion versus those who treated with thrombolytic therapy with failed reperfusion and those who treated with conventional therapy and to correlate between QT dispersion and the complicating serious ventricular arrhythmias following acute myocardial infarction. And it is also performed to assess the influence of age, sex, obesity, smoking, diabetes mellitus, hypertension and site of infarction on QT dispersion. The study included 100 patients with recent acute myocardial infarction and they are classified to 3 groups:Group 1: 30 patients who received streptokinase with successful reperfusion.Group 2: 30 patients who received streptokinase with failed reperfusion.Group 3: 40 patients who did not receive streptokinase (control group).Every patient was subjected to full history taking and thorough clinical examination. Analysis of serum electrolytes (Na, K and ca) was done and cases showing abnormal results were excluded. Serum CPK was checked on admission, after 6 hours, after 12 hours and after 24 hours after onset of thrombolytic therapy. ECG was done for every patient on admission, two hours post thrombolytic therapy and predischarge in groups I and 2. In group 3, ECG was done on admission and predischarge.The study concluded that:1- There is a statistically significant reduction in QT dispersion in patients who received thrombolytic therapy with successful reperfusion versus those who received thrombolytic therapy with failed reperfusion and those who did not receive thrombolytic therapy.2- There is a reduction in the incidence of ventricular arrhythmias in patients with successful reperfusion therapy associated with the reduction in the QT dispersion. So, reduction of QT dispersion may be a mechanism of benefit of thrombolytic therapy.3- QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular arrhythmias.4- QT dispersion is influenced by hypertension, diabetes mellitus, age and site of infarction ,as it is increased in patients with hypertension, diabetes mellitus, age less than 50 years and with anterior than inferior infarction.The study recommended the following:1- Whenever not contraindicated, thrombolytic therapy should be administered as early as possible in cases with AMI.2- QT dispersion can predict the potential for ventricular arrhythmias in patients with AMI.Phakic IOLs despite the excellent initial outcome in terms of predictability and quality of vision imply certain risk for endothelial damage therefore should be followed up regularly. Phakic IOL should be removed as soon as serious decline in endothelial cell density occurs. As large proportion of high myopes will develop cataract, care should be taken to interfere before endothelial cell count decreases below safe limit for performing cataract extraction. The younger the patient at time of PIOL implantation, the higher the endothelial cell count required before PIOL implantation.LASIK is less invasive but irreversible procedure. Concerns about LASIK include degradation in quality of vision especially with marked flattening of the cornea which directly increases the higher order aberrations, the compromise between the optical zone and the possible correction respecting the minimal residual stromal bed. At any cost the risk of post LASIK keratectasia, the most devastating complication of LASIK nowadays, should be minimized. It should be kept in mind that theoretical calculations do not make up for the common error in the flap thickness.Clear lens extraction is more appealing in patients over forty five years especially if there is lens sclerosis as phakic IOL may enhance the cataract. LASIK also complicates IOL calculation should cataract progress necessitating removal. CLE should be performed through as small incision as possible to decrease the fluctuation in anterior chamber depth. Complete cortical clean up as well as capsular polishing must be performed to decrease the incidence of posterior capsular opacification and consequently YAG laser capsulotomy which is a very important added risk factor for retinal detachment in high myopes.Finally, due to the possible risks and elective nature of these procedures, they should only be offered to patients who refuse glasses and do not tolerate contact lenses. Clear explanation and proper informed consent is mandatory in every case.SUMMARYAs refractive surgery gets simpler, safer, more predictable and more effective, it becomes more popular. While cases of simple myopia are usually easy to handle and get satisfactory results when corrected with excimer laser, those with high myopia still represent some challenges.To get the best possible outcome, the surgical plan should be tailored individually to suit each particular case with its peculiar characteristics regarding patients age, activities, visual needs, expectations and of course not the least his own eye parameters.In an attempt to better understand this issue, this study was conducted including ninety eyes of 48 patients, 22 males (45.8 %) and 26 (54.2%) females with a mean age of 40.66±12.03 (range 20 to 63) years and mean spherical equivalent of -12.67±4.64 (range -24 to -7.5) diopters. They were divided into three equal groups.The first group (A) underwent phakic intraocular lens implantation namely Kelman duet lens which is an angle supported anterior chamber phakic lens with rigid tripod haptic and foldable optic that can be injected through a self sealed clear corneal incision of as small size as two mm to be assembled to the previously implanted haptic.The second group (B) under went LASIK after doing the necessary investigations to exclude keratoconus suspects and to make sure that the cornea has enough thickness to allow complete correction of the refractive error in an ablation diameter that matches the scotopic pupil size.The third group (C) underwent clear lens extraction using micro-incision cataract surgery followed by implantation of acrylic foldable posterior chamber IOLs.The mean efficacy index three months postoperatively was 0.99, 0.874 and 0.916 in group A, B and C respectively. UCVA of 0.5 (6/12) or better was achieved in 80%, 93.33%, 63.3% of cases of group A, B and C respectively, while UCVA of 1.0 (6/6) was achieved in 16.67% and 33.3% of cases of group A and B.The mean postoperative safety index was 1.268, 1.03 and 1.249 in group A, B and C respectively. BCVA of 0.5 (6/12) or better was achieved in all cases however, 50%, 60% and 26.67% of cases in group A, B and C respectively achieved postoperative BCVA of 1.0 (6/6)Postoperative spherical equivalent within one diopter of emmetropia was achieved in 76.67%, 86.67%, 70% of cases in group A, B and C respectively. Postoperative defocus equivalent equal to or less than one diopter was achieved in 50%, 80% and 60% of cases group A, B and C respectively.The contrast sensitivity curves improved in the first postoperative month in all spatial frequencies in cases of group A and C without significant change in the subsequent visits. However; in cases of group B the contrast sensitivity curves decreased in the first postoperative month in all spatial frequencies, then improved at the third month visit to the preoperative level to exceed it in the sixth month without significant change in the subsequent ninth month visit.There was transient rise in IOP in cases of group A and C during the first postoperative week however; in group B IOP showed significant decline all through the follow up period.There was statistically significant loss of endothelial cells at one and nine months postoperatively however, the degree of loss varied in different groups. The loss in the mean endothelial cell count from preoperative level to the first month postoperatively was 6.29%, 1.56% and 9.78% and from the first month to the ninth month postoperatively was 0.99%, 1.28% and 0.92% in group A, B and C respectively.Regarding complications; in group (A), 6.67% of cases developed mild intraoperative hyphaema. Pupil ovalization occurred in 6.67% of cases, In 3.33% of cases rotation of the lens occurred due to too short haptics. In group (B), 3.33% of cases had decentered flap 3.33 % had decentered ablation. Interface deposits as well as bleeding to the interface were observed in 6.67%. The incidence of epithelial ingrowth, DLK and flap stria was 3.33% where as that of pseudoDLK was 6.67%. while in group (C), 3.33% of cases had intraoperative iris trauma while developed 6.67% posterior capsule opacification.CONCLUSIONSurgical correction of moderate to high myopia proved to be effective, safe and predictable. The choice of the procedure should be based on the patient’s condition, the surgeon’s expertise as well as the resources of the health care facility. The main procedures for correction of high myopia are Phakic IOLs, LASIK and clear lens extraction. Each of these procedures has its own indications, precautions as well as its most feared complications.Phakic IOLs despite the excellent initial outcome in terms of predictability and quality of vision imply certain risk for endothelial damage therefore should be followed up regularly. Phakic IOL should be removed as soon as serious decline in endothelial cell density occurs. As large proportion of high myopes will develop cataract, care should be taken to interfere before endothelial cell count decreases below safe limit for performing cataract extraction. The younger the patient at time of PIOL implantation, the higher the endothelial cell count required before PIOL implantation.LASIK is less invasive but irreversible procedure. Concerns about LASIK include degradation in quality of vision especially with marked flattening of the cornea which directly increases the higher order aberrations, the compromise between the optical zone and the possible correction respecting the minimal residual stromal bed. At any cost the risk of post LASIK keratectasia, the most devastating complication of LASIK nowadays, should be minimized. It should be kept in mind that theoretical calculations do not make up for the common error in the flap thickness.Clear lens extraction is more appealing in patients over forty five years especially if there is lens sclerosis as phakic IOL may enhance the cataract. LASIK also complicates IOL calculation should cataract progress necessitating removal. CLE should be performed through as small incision as possible to decrease the fluctuation in anterior chamber depth. Complete cortical clean up as well as capsular polishing must be performed to decrease the incidence of posterior capsular opacification and consequently YAG laser capsulotomy which is a very important added risk factor for retinal detachment in high myopes.Finally, due to the possible risks and elective nature of these procedures, they should only be offered to patients who refuse glasses and do not tolerate contact lenses. Clear explanation and proper informed consent is mandatory in every case.SUMMARYAs refractive surgery gets simpler, safer, more predictable and more effective, it becomes more popular. While cases of simple myopia are usually easy to handle and get satisfactory results when corrected with excimer laser, those with high myopia still represent some challenges.To get the best possible outcome, the surgical plan should be tailored individually to suit each particular case with its peculiar characteristics regarding patients age, activities, visual needs, expectations and of course not the least his own eye parameters.In an attempt to better understand this issue, this study was conducted including ninety eyes of 48 patients, 22 males (45.8 %) and 26 (54.2%) females with a mean age of 40.66±12.03 (range 20 to 63) years and mean spherical equivalent of -12.67±4.64 (range -24 to -7.5) diopters. They were divided into three equal groups.The first group (A) underwent phakic intraocular lens implantation namely Kelman duet lens which is an angle supported anterior chamber phakic lens with rigid tripod haptic and foldable optic that can be injected through a self sealed clear corneal incision of as small size as two mm to be assembled to the previously implanted haptic.The second group (B) under went LASIK after doing the necessary investigations to exclude keratoconus suspects and to make sure that the cornea has enough thickness to allow complete correction of the refractive error in an ablation diameter that matches the scotopic pupil size.The third group (C) underwent clear lens extraction using micro-incision cataract surgery followed by implantation of acrylic foldable posterior chamber IOLs.The mean efficacy index three months postoperatively was 0.99, 0.874 and 0.916 in group A, B and C respectively. UCVA of 0.5 (6/12) or better was achieved in 80%, 93.33%, 63.3% of cases of group A, B and C respectively, while UCVA of 1.0 (6/6) was achieved in 16.67% and 33.3% of cases of group A and B.The mean postoperative safety index was 1.268, 1.03 and 1.249 in group A, B and C respectively. BCVA of 0.5 (6/12) or better was achieved in all cases however, 50%, 60% and 26.67% of cases in group A, B and C respectively achieved postoperative BCVA of 1.0 (6/6)Postoperative spherical equivalent within one diopter of emmetropia was achieved in 76.67%, 86.67%, 70% of cases in group A, B and C respectively. Postoperative defocus equivalent equal to or less than one diopter was achieved in 50%, 80% and 60% of cases group A, B and C respectively.The contrast sensitivity curves improved in the first postoperative month in all spatial frequencies in cases of group A and C without significant change in the subsequent visits. However; in cases of group B the contrast sensitivity curves decreased in the first postoperative month in all spatial frequencies, then improved at the third month visit to the preoperative level to exceed it in the sixth month without significant change in the subsequent ninth month visit.There was transient rise in IOP in cases of group A and C during the first postoperative week however; in group B IOP showed significant decline all through the follow up period.There was statistically significant loss of endothelial cells at one and nine months postoperatively however, the degree of loss varied in different groups. The loss in the mean endothelial cell count from preoperative level to the first month postoperatively was 6.29%, 1.56% and 9.78% and from the first month to the ninth month postoperatively was 0.99%, 1.28% and 0.92% in group A, B and C respectively.Regarding complications; in group (A), 6.67% of cases developed mild intraoperative hyphaema. Pupil ovalization occurred in 6.67% of cases, In 3.33% of cases rotation of the lens occurred due to too short haptics. In group (B), 3.33% of cases had decentered flap 3.33 % had decentered ablation. Interface deposits as well as bleeding to the interface were observed in 6.67%. The incidence of epithelial ingrowth, DLK and flap stria was 3.33% where as that of pseudoDLK was 6.67%. while in group (C), 3.33% of cases had intraoperative iris trauma while developed 6.67% posterior capsule opacification.CONCLUSIONSurgical correction of moderate to high myopia proved to be effective, safe and predictable. The choice of the procedure should be based on the patient’s condition, the surgeon’s expertise as well as the resources of the health care facility. The main procedures for correction of high myopia are Phakic IOLs, LASIK and clear lens extraction. Each of these procedures has its own indications, precautions as well as its most feared complications.Phakic IOLs despite the excellent initial outcome in terms of predictability and quality of vision imply certain risk for endothelial damage therefore should be followed up regularly. Phakic IOL should be removed as soon as serious decline in endothelial cell density occurs. As large proportion of high myopes will develop cataract, care should be taken to interfere before endothelial cell count decreases below safe limit for performing cataract extraction. The younger the patient at time of PIOL implantation, the higher the endothelial cell count required before PIOL implantation.LASIK is less invasive but irreversible procedure. Concerns about LASIK include degradation in quality of vision especially with marked flattening of the cornea which directly increases the higher order aberrations, the compromise between the optical zone and the possible correction respecting the minimal residual stromal bed. At any cost the risk of post LASIK keratectasia, the most devastating complication of LASIK nowadays, should be minimized. It should be kept in mind that theoretical calculations do not make up for the common error in the flap thickness.Clear lens extraction is more appealing in patients over forty five years especially if there is lens sclerosis as phakic IOL may enhance the cataract. LASIK also complicates IOL calculation should cataract progress necessitating removal. CLE should be performed through as small incision as possible to decrease the fluctuation in anterior chamber depth. Complete cortical clean up as well as capsular polishing must be performed to decrease the incidence of posterior capsular opacification and consequently YAG laser capsulotomy which is a very important added risk factor for retinal detachment in high myopes.Finally, due to the possible risks and elective nature of these procedures, they should only be offered to patients who refuse glasses and do not tolerate contact lenses. Clear explanation and proper informed consent is mandatory in every case.SUMMARYAs refractive surgery gets simpler, safer, more predictable and more effective, it becomes more popular. While cases of simple myopia are usually easy to handle and get satisfactory results when corrected with excimer laser, those with high myopia still represent some challenges.To get the best possible outcome, the surgical plan should be tailored individually to suit each particular case with its peculiar characteristics regarding patients age, activities, visual needs, expectations and of course not the least his own eye parameters.In an attempt to better understand this issue, this study was conducted including ninety eyes of 48 patients, 22 males (45.8 %) and 26 (54.2%) females with a mean age of 40.66±12.03 (range 20 to 63) years and mean spherical equivalent of -12.67±4.64 (range -24 to -7.5) diopters. They were divided into three equal groups.The first group (A) underwent phakic intraocular lens implantation namely Kelman duet lens which is an angle supported anterior chamber phakic lens with rigid tripod haptic and foldable optic that can be injected through a self sealed clear corneal incision of as small size as two mm to be assembled to the previously implanted haptic.The second group (B) under went LASIK after doing the necessary investigations to exclude keratoconus suspects and to make sure that the cornea has enough thickness to allow complete correction of the refractive error in an ablation diameter that matches the scotopic pupil size.The third group (C) underwent clear lens extraction using micro-incision cataract surgery followed by implantation of acrylic foldable posterior chamber IOLs.The mean efficacy index three months postoperatively was 0.99, 0.874 and 0.916 in group A, B and C respectively. UCVA of 0.5 (6/12) or better was achieved in 80%, 93.33%, 63.3% of cases of group A, B and C respectively, while UCVA of 1.0 (6/6) was achieved in 16.67% and 33.3% of cases of group A and B.The mean postoperative safety index was 1.268, 1.03 and 1.249 in group A, B and C respectively. BCVA of 0.5 (6/12) or better was achieved in all cases however, 50%, 60% and 26.67% of cases in group A, B and C respectively achieved postoperative BCVA of 1.0 (6/6)Postoperative spherical equivalent within one diopter of emmetropia was achieved in 76.67%, 86.67%, 70% of cases in group A, B and C respectively. Postoperative defocus equivalent equal to or less than one diopter was achieved in 50%, 80% and 60% of cases group A, B and C respectively.The contrast sensitivity curves improved in the first postoperative month in all spatial frequencies in cases of group A and C without significant change in the subsequent visits. However; in cases of group B the contrast sensitivity curves decreased in the first postoperative month in all spatial frequencies, then improved at the third month visit to the preoperative level to exceed it in the sixth month without significant change in the subsequent ninth month visit.There was transient rise in IOP in cases of group A and C during the first postoperative week however; in group B IOP showed significant decline all through the follow up period.There was statistically significant loss of endothelial cells at one and nine months postoperatively however, the degree of loss varied in different groups. The loss in the mean endothelial cell count from preoperative level to the first month postoperatively was 6.29%, 1.56% and 9.78% and from the first month to the ninth month postoperatively was 0.99%, 1.28% and 0.92% in group A, B and C respectively.Regarding complications; in group (A), 6.67% of cases developed mild intraoperative hyphaema. Pupil ovalization occurred in 6.67% of cases, In 3.33% of cases rotation of the lens occurred due to too short haptics. In group (B), 3.33% of cases had decentered flap 3.33 % had decentered ablation. Interface deposits as well as bleeding to the interface were observed in 6.67%. The incidence of epithelial ingrowth, DLK and flap stria was 3.33% where as that of pseudoDLK was 6.67%. while in group (C), 3.33% of cases had intraoperative iris trauma while developed 6.67% posterior capsule opacification.CONCLUSIONSurgical correction of moderate to high myopia proved to be effective, safe and predictable. The choice of the procedure should be based on the patient’s condition, the surgeon’s expertise as well as the resources of the health care facility. The main procedures for correction of high myopia are Phakic IOLs, LASIK and clear lens extraction. Each of these procedures has its own indications, precautions as well as its most feared complications.Phakic IOLs despite the excellent initial outcome in terms of predictability and quality of vision imply certain risk for endothelial damage therefore should be followed up regularly. Phakic IOL should be removed as soon as serious decline in endothelial cell density occurs. As large proportion of high myopes will develop cataract, care should be taken to interfere before endothelial cell count decreases below safe limit for performing cataract extraction. The younger the patient at time of PIOL implantation, the higher the endothelial cell count required before PIOL implantation.LASIK is less invasive but irreversible procedure. Concerns about LASIK include degradation in quality of vision especially with marked flattening of the cornea which directly increases the higher order aberrations, the compromise between the optical zone and the possible correction respecting the minimal residual stromal bed. At any cost the risk of post LASIK keratectasia, the most devastating complication of LASIK nowadays, should be minimized. It should be kept in mind that theoretical calculations do not make up for the common error in the flap thickness.Clear lens extraction is more appealing in patients over forty five years especially if there is lens sclerosis as phakic IOL may enhance the cataract. LASIK also complicates IOL calculation should cataract progress necessitating removal. CLE should be performed through as small incision as possible to decrease the fluctuation in anterior chamber depth. Complete cortical clean up as well as capsular polishing must be performed to decrease the incidence of posterior capsular opacification and consequently YAG laser capsulotomy which is a very important added risk factor for retinal detachment in high myopes.Finally, due to the possible risks and elective nature of these procedures, they should only be offered to patients who refuse glasses and do not tolerate contact lenses. Clear explanation and proper informed consent is mandatory in every case.SUMMARYAs refractive surgery gets simpler, safer, more predictable and more effective, it becomes more popular. While cases of simple myopia are usually easy to handle and get satisfactory results when corrected with excimer laser, those with high myopia still represent some challenges.To get the best possible outcome, the surgical plan should be tailored individually to suit each particular case with its peculiar characteristics regarding patients age, activities, visual needs, expectations and of course not the least his own eye parameters.In an attempt to better understand this issue, this study was conducted including ninety eyes of 48 patients, 22 males (45.8 %) and 26 (54.2%) females with a mean age of 40.66±12.03 (range 20 to 63) years and mean spherical equivalent of -12.67±4.64 (range -24 to -7.5) diopters. They were divided into three equal groups.The first group (A) underwent phakic intraocular lens implantation namely Kelman duet lens which is an angle supported anterior chamber phakic lens with rigid tripod haptic and foldable optic that can be injected through a self sealed clear corneal incision of as small size as two mm to be assembled to the previously implanted haptic.The second group (B) under went LASIK after doing the necessary investigations to exclude keratoconus suspects and to make sure that the cornea has enough thickness to allow complete correction of the refractive error in an ablation diameter that matches the scotopic pupil size.The third group (C) underwent clear lens extraction using micro-incision cataract surgery followed by implantation of acrylic foldable posterior chamber IOLs.The mean efficacy index three months postoperatively was 0.99, 0.874 and 0.916 in group A, B and C respectively. UCVA of 0.5 (6/12) or better was achieved in 80%, 93.33%, 63.3% of cases of group A, B and C respectively, while UCVA of 1.0 (6/6) was achieved in 16.67% and 33.3% of cases of group A and B.The mean postoperative safety index was 1.268, 1.03 and 1.249 in group A, B and C respectively. BCVA of 0.5 (6/12) or better was achieved in all cases however, 50%, 60% and 26.67% of cases in group A, B and C respectively achieved postoperative BCVA of 1.0 (6/6)Postoperative spherical equivalent within one diopter of emmetropia was achieved in 76.67%, 86.67%, 70% of cases in group A, B and C respectively. Postoperative defocus equivalent equal to or less than one diopter was achieved in 50%, 80% and 60% of cases group A, B and C respectively.The contrast sensitivity curves improved in the first postoperative month in all spatial frequencies in cases of group A and C without significant change in the subsequent visits. However; in cases of group B the contrast sensitivity curves decreased in the first postoperative month in all spatial frequencies, then improved at the third month visit to the preoperative level to exceed it in the sixth month without significant change in the subsequent ninth month visit.There was transient rise in IOP in cases of group A and C during the first postoperative week however; in group B IOP showed significant decline all through the follow up period.There was statistically significant loss of endothelial cells at one and nine months postoperatively however, the degree of loss varied in different groups. The loss in the mean endothelial cell count from preoperative level to the first month postoperatively was 6.29%, 1.56% and 9.78% and from the first month to the ninth month postoperatively was 0.99%, 1.28% and 0.92% in group A, B and C respectively.Regarding complications; in group (A), 6.67% of cases developed mild intraoperative hyphaema. Pupil ovalization occurred in 6.67% of cases, In 3.33% of cases rotation of the lens occurred due to too short haptics. In group (B), 3.33% of cases had decentered flap 3.33 % had decentered ablation. Interface deposits as well as bleeding to the interface were observed in 6.67%. The incidence of epithelial ingrowth, DLK and flap stria was 3.33% where as that of pseudoDLK was 6.67%. while in group (C), 3.33% of cases had intraoperative iris trauma while developed 6.67% posterior capsule opacification.CONCLUSIONSurgical correction of moderate to high myopia proved to be effective, safe and predictable. The choice of the procedure should be based on the patient’s condition, the surgeon’s expertise as well as the resources of the health care facility. The main procedures for correction of high myopia are Phakic IOLs, LASIK and clear lens extraction. Each of these procedures has its own indications, precautions as well as its most feared complications.Phakic IOLs despite the excellent initial outcome in terms of predictability and quality of vision imply certain risk for endothelial damage therefore should be followed up regularly. Phakic IOL should be removed as soon as serious decline in endothelial cell density occurs. As large proportion of high myopes will develop cataract, care should be taken to interfere before endothelial cell count decreases below safe limit for performing cataract extraction. The younger the patient at time of PIOL implantation, the higher the endothelial cell count required before PIOL implantation.LASIK is less invasive but irreversible procedure. Concerns about LASIK include degradation in quality of vision especially with marked flattening of the cornea which directly increases the higher order aberrations, the compromise between the optical zone and the possible correction respecting the minimal residual stromal bed. At any cost the risk of post LASIK keratectasia, the most devastating complication of LASIK nowadays, should be minimized. It should be kept in mind that theoretical calculations do not make up for the common error in the flap thickness.Clear lens extraction is more appealing in patients over forty five years especially if there is lens sclerosis as phakic IOL may enhance the cataract. LASIK also complicates IOL calculation should cataract progress necessitating removal. CLE should be performed through as small incision as possible to decrease the fluctuation in anterior chamber depth. Complete cortical clean up as well as capsular polishing must be performed to decrease the incidence of posterior capsular opacification and consequently YAG laser capsulotomy which is a very important added risk factor for retinal detachment in high myopes.Finally, due to the possible risks and elective nature of these procedures, they should only be offered to patients who refuse glasses and do not tolerate contact lenses. Clear explanation and proper informed consent is mandatory in every case.SUMMARYAs refractive surgery gets simpler, safer, more predictable and more effective, it becomes more popular. While cases of simple myopia are usually easy to handle and get satisfactory results when corrected with excimer laser, those with high myopia still represent some challenges.To get the best possible outcome, the surgical plan should be tailored individually to suit each particular case with its peculiar characteristics regarding patients age, activities, visual needs, expectations and of course not the least his own eye parameters.In an attempt to better understand this issue, this study was conducted including ninety eyes of 48 patients, 22 males (45.8 %) and 26 (54.2%) females with a mean age of 40.66±12.03 (range 20 to 63) years and mean spherical equivalent of -12.67±4.64 (range -24 to -7.5) diopters. They were divided into three equal groups.The first group (A) underwent phakic intraocular lens implantation namely Kelman duet lens which is an angle supported anterior chamber phakic lens with rigid tripod haptic and foldable optic that can be injected through a self sealed clear corneal incision of as small size as two mm to be assembled to the previously implanted haptic.The second group (B) under went LASIK after doing the necessary investigations to exclude keratoconus suspects and to make sure that the cornea has enough thickness to allow complete correction of the refractive error in an ablation diameter that matches the scotopic pupil size.The third group (C) underwent clear lens extraction using micro-incision cataract surgery followed by implantation of acrylic foldable posterior chamber IOLs.The mean efficacy index three months postoperatively was 0.99, 0.874 and 0.916 in group A, B and C respectively. UCVA of 0.5 (6/12) or better was achieved in 80%, 93.33%, 63.3% of cases of group A, B and C respectively, while UCVA of 1.0 (6/6) was achieved in 16.67% and 33.3% of cases of group A and B.The mean postoperative safety index was 1.268, 1.03 and 1.249 in group A, B and C respectively. BCVA of 0.5 (6/12) or better was achieved in all cases however, 50%, 60% and 26.67% of cases in group A, B and C respectively achieved postoperative BCVA of 1.0 (6/6)Postoperative spherical equivalent within one diopter of emmetropia was achieved in 76.67%, 86.67%, 70% of cases in group A, B and C respectively. Postoperative defocus equivalent equal to or less than one diopter was achieved in 50%, 80% and 60% of cases group A, B and C respectively.The contrast sensitivity curves improved in the first postoperative month in all spatial frequencies in cases of group A and C without significant change in the subsequent visits. However; in cases of group B the contrast sensitivity curves decreased in the first postoperative month in all spatial frequencies, then improved at the third month visit to the preoperative level to exceed it in the sixth month without significant change in the subsequent ninth month visit.There was transient rise in IOP in cases of group A and C during the first postoperative week however; in group B IOP showed significant decline all through the follow up period.There was statistically significant loss of endothelial cells at one and nine months postoperatively however, the degree of loss varied in different groups. The loss in the mean endothelial cell count from preoperative level to the first month postoperatively was 6.29%, 1.56% and 9.78% and from the first month to the ninth month postoperatively was 0.99%, 1.28% and 0.92% in group A, B and C respectively.Regarding complications; in group (A), 6.67% of cases developed mild intraoperative hyphaema. Pupil ovalization occurred in 6.67% of cases, In 3.33% of cases rotation of the lens occurred due to too short haptics. In group (B), 3.33% of cases had decentered flap 3.33 % had decentered ablation. Interface deposits as well as bleeding to the interface were observed in 6.67%. The incidence of epithelial ingrowth, DLK and flap stria was 3.33% where as that of pseudoDLK was 6.67%. while in group (C), 3.33% of cases had intraoperative iris trauma while developed 6.67% posterior capsule opacification.CONCLUSIONSurgical correction of moderate to high myopia proved to be effective, safe and predictable. The choice of the procedure should be based on the patient’s condition, the surgeon’s expertise as well as the resources of the health care facility. The main procedures for correction of high myopia are Phakic IOLs, LASIK and clear lens extraction. Each of these procedures has its own indications, precautions as well as its most feared complications.Phakic IOLs despite the excellent initial outcome in terms of predictability and quality of vision imply certain risk for endothelial damage therefore should be followed up regularly. Phakic IOL should be removed as soon as serious decline in endothelial cell density occurs. As large proportion of high myopes will develop cataract, care should be taken to interfere before endothelial cell count decreases below safe limit for performing cataract extraction. The younger the patient at time of PIOL implantation, the higher the endothelial cell count required before PIOL implantation.LASIK is less invasive but irreversible procedure. Concerns about LASIK include degradation in quality of vision especially with marked flattening of the cornea which directly increases the higher order aberrations, the compromise between the optical zone and the possible correction respecting the minimal residual stromal bed. At any cost the risk of post LASIK keratectasia, the most devastating complication of LASIK nowadays, should be minimized. It should be kept in mind that theoretical calculations do not make up for the common error in the flap thickness.Clear lens extraction is more appealing in patients over forty five years especially if there is lens sclerosis as phakic IOL may enhance the cataract. LASIK also complicates IOL calculation should cataract progress necessitating removal. CLE should be performed through as small incision as possible to decrease the fluctuation in anterior chamber depth. Complete cortical clean up as well as capsular polishing must be performed to decrease the incidence of posterior capsular opacification and consequently YAG laser capsulotomy which is a very important added risk factor for retinal detachment in high myopes.Finally, due to the possible risks and elective nature of these procedures, they should only be offered to patients who refuse glasses and do not tolerate contact lenses. Clear explanation and proper informed consent is mandatory in every case.SUMMARYAs refractive surgery gets simpler, safer, more predictable and more effective, it becomes more popular. While cases of simple myopia are usually easy to handle and get satisfactory results when corrected with excimer laser, those with high myopia still represent some challenges.To get the best possible outcome, the surgical plan should be tailored individually to suit each particular case with its peculiar characteristics regarding patients age, activities, visual needs, expectations and of course not the least his own eye parameters.In an attempt to better understand this issue, this study was conducted including ninety eyes of 48 patients, 22 males (45.8 %) and 26 (54.2%) females with a mean age of 40.66±12.03 (range 20 to 63) years and mean spherical equivalent of -12.67±4.64 (range -24 to -7.5) diopters. They were divided into three equal groups.The first group (A) underwent phakic intraocular lens implantation namely Kelman duet lens which is an angle supported anterior chamber phakic lens with rigid tripod haptic and foldable optic that can be injected through a self sealed clear corneal incision of as small size as two mm to be assembled to the previously implanted haptic.The second group (B) under went LASIK after doing the necessary investigations to exclude keratoconus suspects and to make sure that the cornea has enough thickness to allow complete correction of the refractive error in an ablation diameter that matches the scotopic pupil size.The third group (C) underwent clear lens extraction using micro-incision cataract surgery followed by implantation of acrylic foldable posterior chamber IOLs.mothers positive for ochratoxin and/or aflatoxin versus negative ones.11- There is statistically significant difference in prothrombin time inmothers’serum positive for aflatoxin.