In order to increase the sensitivity of diagnosis without treating unnecessarily, it is best to be liberal in looking for preterm labor, but conservative in diagnosis and treatment. The goal of first contact with a patient who may have preterm labor and d1. Invite any patient complaining of possible symptoms of preterm labor to come in for contraction monitoring and cervical exam. Severity of symptoms bears little relation to their clinical significance.2. Wait for cervical change of at least 1 cm in dilatation of 2 cm or more before accepting the diagnosis of preterm labor in a patient with persistent contractions.3. Use cervical sonography (cervix > 30 mm) as a test to support continued observation.4. Be wary of ”incidental” diagnosis of preterm labor especially in the afternoon and early evening. Remember the wide range of contraction frequency and the normal increase in contractions in the late afternoon and evening in normal pregnancy.* Women at increased risk of preterm delivery may be identified byvarious risk factors in the obstetric history.* Antenatal care. Good antenatal care is important in the prevention of preterm delivery.* Women whose work requires prolonged standing or walking should be monitored carefully throughout pregnancy for evidence of intrauterine growth restriction or symptoms of preterm labor.# The following prenatal and antenatal interventions in preventingPAD:*Home and/or ambulatory uterine activity monitoring.*Nutrition and vitamin supplementations.*Psychosocial support and home visitation.*PAD education.*Bed rest.*Hydration.*Reducing excess manual labor and psychological stress.*Ensuring body mass index is greater than 20 kg / m2 before conception* Rest. Advice on bed rest and abstinence from sexual intercourse should be given to the high risk patient.* In selected patients, prophylactic cervical cerclage and antibiotic treatment of women with bacterial vaginosis may be associated with a reduction in preterm delivery.* Home uterine activity monitoring should be considered as an aid in the management of women with singletons gestation who have risk factors, such as a prior preterm birth, associated with an increased rate of preterm delivery.- The initial hospital management of patients in preterm labor is the real important factor behind continuation of pregnancy.- Medical therapy used to inhibit labor should be discontinued if labor progresses.- Ritodrine provided more effective tocolysis within the first 48 h than nifedipine at the doses used, although with a significantly higher rate of side effects.Intravenous beta- agonists administered between 20 and 36 weeksof gestation are useful in achieving uterine tocolysis in premature labor.- Beta- agonists should be used to delay delivery for 24 to 48 hoursin order to administer corticosteroids to promote fetal lung maturity.A- Beta- agonists should be administered via a controlled infusiondevice. The infusion rate should be increased at regular intervals until contractions have ceased or until the maternal pulse reaches 130- 140 per minute.- Maternal corticosteroids administration is beneficial in the pretermpatient to reduce the incidence of Respiratory Distress Syndrome in the newborn.Delivery of the preterm fetus should be in an obstetric unit with neonatal intensive care facilities. Fetal monitoring during labor is important to ensure fetal well-being.