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Tissue-specific methylation of human insulin gene and PCR assay for monitoring Beta cell death
Faculty
Pharmacy
Year:
2014
Type of Publication:
ZU Hosted
Pages:
Authors:
Mohammed Ibrahim Huseni
Staff Zu Site
Abstract In Staff Site
Journal:
PLOS ONE PLOS ONE
Volume:
4
Keywords :
Tissue-specific methylation , human insulin gene , , assay
Abstract:
The onset of metabolic dysregulation in type 1 diabetes (T1D) occurs after autoimmune destruction of the majority of pancreatic insulin-producing beta cells. We previously demonstrated that the DNA encoding the insulin gene is uniquely unme
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