Development of a quantitative methylation-specific polymerase chain reaction method for monitoring beta cell death in type 1 diabetes

Faculty Pharmacy Year: 2012
Type of Publication: ZU Hosted Pages: 1-11
Authors:
Journal: PLOS ONE PLOS ONE Volume: 10
Keywords : Development , , quantitative methylation-specific polymerase chain reaction    
Abstract:
DNA methylation is a mechanism by which cells control gene expression, and cell-specific genes often exhibit unique patterns of DNA methylation. We previously reported that the mouse insulin-2 gene (Ins2) promoter has three potential methyl
   
     
 
       

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