Synthesis and Biological Evaluation of Some N-Arylpyrazoles and Pyrazolo[3,4-d]pyridazines as Anti-Inflammatory Agents

Faculty Pharmacy Year: 2013
Type of Publication: ZU Hosted Pages: 688–698
Authors:
Osama Ibrahim Abdou Elsabagh
Journal: Arch. Pharm. Chem. Life Sci. 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim Volume:
Keywords : Synthesis , Biological Evaluation , Some N-Arylpyrazoles , Pyrazolo[3,4-d]pyridazines    
Abstract:
A series of 3,4-bis-chalcone-N-arylpyrazoles 3a–k was prepared from diacetyl pyrazoles 2a–e. The reaction of 2d and 2e with hydrazine hydrate gave pyrazolo[3,4-d]pyridazine derivatives 4a–b. Furthermore, the reaction of 2a–e with thiosemica
    
     
 
       

Author Related Publications

  • Osama Ibrahim Abdou Elsabagh, "Design, synthesis and antitumor evaluation of novel pyrazolo[3,4-d]pyrimidines incorporating different amino acid conjugates as potential DHFR inhibitors", Taylor & Francis Group, 2022 More
  • Osama Ibrahim Abdou Elsabagh, "Synthesis of Some New Benzisothiazolone and Benzenesulfonamide Derivatives of Biological Interest Starting from Saccharin Sodium", 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim, 2013 More
  • Osama Ibrahim Abdou Elsabagh, "Synthesis of new benzotriazepin-5(2H)-one derivatives of expected antipsychotic activity", springer, 2012 More
  • Osama Ibrahim Abdou Elsabagh, "Synthesis and pharmacological studies for some new benzotriazole and dibenzodiazepine derivatives as antipsychotic agents", KOREAN CHEMICAL SOC, 2009 More
  • Osama Ibrahim Abdou Elsabagh, "Synthesis and antiviral activity of new pyrazole and thiazole derivatives", Elsevier Masson SAS., 2009 More

Department Related Publications

  • Mansour Alsayed Mansour Abokol, "SYNTHESIS OF 3- SUBSTITUTED (6-BROMO-2-IMIDAZO {4, 5- B} PYRIDINYL) PROPIONIC ACID AS ANTIINFLAMMATORY, ANALGESIC, AND ANTIPYTRIC AGENTS", Zag. J. Pharm. Sci., Vol. 1 No. 1 Nov. Pp 129-139 June, 1993 More
  • Noha Ibrahiem Elsayed Mohamed Zidain, "Developing a High-performance Liquid Chromatography Method for Simultaneous Determination of Loratadine and its Metabolite Desloratadine in Human Plasma", benthamscience, 2020 More
  • Mahmoud Mohamed Mohamed Sebaee, "Developing a High-performance Liquid Chromatography Method for Simultaneous Determination of Loratadine and its Metabolite Desloratadine in Human Plasma", benthamscience, 2020 More
  • Sobhi Mohamed Mahmoud Ibrahym, "47. Hplc determination of three cephalosporines (cefipime, ceftriaxone , cefotaxime) in their bulk and dosage form", Asian J .Pharm. Ana., 2014 More
  • Ahmed Samy Abdelsamad Abdelkhalek hilal, "Triple targeting of mutant EGFRL858R/T790M, COX-2, and 15-LOX: design and synthesis of novel quinazolinone tethered phenyl urea derivatives for anti-inflammatory and anticancer evaluation", Taylor and francis, 2023 More
Tweet