Development and optimization of on-line 2-dimensional chromatographic approaches for eliminating matrix effects and improving bioanalysis of peptides in human plasma using UHPLC-MS/MS

Faculty Pharmacy Year: 2013
Type of Publication: ZU Hosted Pages: 415–425
Authors:
Journal: Drug Testing and Analysis USA Volume:
Keywords : Development , optimization , on-line 2-dimensional chromatographic approaches for eliminating    
Abstract:
Online 2-dimensional chromatographic approaches for eliminating matrix effects and optimizing bioanalysis of peptides using ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) were studied. Three therapeuti
   
     
 
       

Author Related Publications

  • Omnia Ahmed Emam Ismaiel, "Non-extractive spectrophotometric determination of memantine HCl, clomipramine HCl and fluvoxamine maleate in pure form and in pharmaceutical products by ion-pair complex formation with rose Bengal.", ScienceDirect, 2020 More
  • Omnia Ahmed Emam Ismaiel, "Monitoring phospholipids for assessment of matrix effects in a liquid chromatography–tandem mass spectrometry method for hydrocodone and pseudoephedrine in human plasma", USA, 2007 More
  • Omnia Ahmed Emam Ismaiel, "Monitoring phospholipids for assessment of ion enhancement and ion suppression in ESI and APCI LC/MS/MS for chlorpheniramine in human plasma and the importance of multiple source matrix effect evaluations", USA, 2008 More
  • Omnia Ahmed Emam Ismaiel, "Assessment of matrix effects and determination of niacin in human plasma using liquid–liquid extraction and liquid chromatography–tandem mass spectrometry", USA, 2008 More
  • Omnia Ahmed Emam Ismaiel, "Development of a Liquid Chromatography-Negative ESI-Tandem Mass Spectrometry Method for Ibuprofen with Minimization of Matrix Effects Associated with Phospholipids", USA, 2008 More

Department Related Publications

  • Hawaa Mohamed Khalil Salem Khalil, "Analytical Study of Protein of Milk & Milk Products ", لايوجد, 1900 More
  • Magda Mohamed Elsayed Elhenawy, " New Methods for the Quantitative Determination of Certain Antihistaminic Drugs&Their Application in Pharmaceutical Preparations ", لايوجد, 1900 More
  • Hisham Abdelaziz Mohamed Hashime, "The effect of the process variables on the HPLC separation of tricyclic neuroleptics on calixarene-bonded statinary phase", لايوجد, 1900 More
  • Naglaa Abdelsatar Mohamed, "Utility of molybdophosphoric acid in qualitative and quantitative analysis of Sibutramine HCl, Sumatribtan succinate and Lomefloxacine HCl", international, 2012 More
  • Hisham Ezzat Abdelattef Ibrahiem, "Utility of molybdophosphoric acid in qualitative and quantitative analysis of Sibutramine HCl, Sumatribtan succinate and Lomefloxacine HCl", international, 2012 More
Tweet