Determination of Glibenclamide and Metformin Hydrochloride in active Pharmaceutical Ingredients and Combined Dosage Form Using a Stability- Indicating HPLC-UV Method

Faculty Pharmacy Year: 2013
Type of Publication: ZU Hosted Pages: 716-721
Authors:
Omnia Ahmed Emam Ismaiel
Journal: Asian Journal of Research in Chemistry International Volume:
Keywords : Determination , Glibenclamide , Metformin Hydrochloride , active Pharmaceutical Ingredients    
Abstract:
A simple, precise and accurate isocratic reversed-phase stability-indicating HPLC method was developed and validated for the determination of glibenclamide (GLB) and metformin hydrochloride (MET) in pure active pharmaceutical ingredients
    
     
 
       

Author Related Publications

  • Omnia Ahmed Emam Ismaiel, "Non-extractive spectrophotometric determination of memantine HCl, clomipramine HCl and fluvoxamine maleate in pure form and in pharmaceutical products by ion-pair complex formation with rose Bengal.", ScienceDirect, 2020 More
  • Omnia Ahmed Emam Ismaiel, "Monitoring phospholipids for assessment of matrix effects in a liquid chromatography–tandem mass spectrometry method for hydrocodone and pseudoephedrine in human plasma", USA, 2007 More
  • Omnia Ahmed Emam Ismaiel, "Monitoring phospholipids for assessment of ion enhancement and ion suppression in ESI and APCI LC/MS/MS for chlorpheniramine in human plasma and the importance of multiple source matrix effect evaluations", USA, 2008 More
  • Omnia Ahmed Emam Ismaiel, "Assessment of matrix effects and determination of niacin in human plasma using liquid–liquid extraction and liquid chromatography–tandem mass spectrometry", USA, 2008 More
  • Omnia Ahmed Emam Ismaiel, "Development of a Liquid Chromatography-Negative ESI-Tandem Mass Spectrometry Method for Ibuprofen with Minimization of Matrix Effects Associated with Phospholipids", USA, 2008 More

Department Related Publications

  • Rania Adel Sayed Ahmd, "QbD-steered HPTLC approach for concurrent estimation of six co-administered COVID-19 and cardiovascular drugs in different matrices: greenness appraisal", Springer, 2025 More
  • Abdallah Abdelaziem Abdallah Shlabi , "QbD-steered HPTLC approach for concurrent estimation of six co-administered COVID-19 and cardiovascular drugs in different matrices: greenness appraisal", Springer, 2025 More
  • Yasmin Ahmed Ibrahim, "Application of poly-dl-methionine/gold nanoparticle-modified recycled battery graphite as an eco-friendly electrochemical sensor for the spasmolytic drug vincamine", Royal Society of Chemistry, 2026 More
  • Naglaa Abdelsatar Mohamed, "Application of poly-dl-methionine/gold nanoparticle-modified recycled battery graphite as an eco-friendly electrochemical sensor for the spasmolytic drug vincamine", Royal Society of Chemistry, 2026 More
  • Hisham Ezzat Abdelattef Ibrahiem, "Application of poly-dl-methionine/gold nanoparticle-modified recycled battery graphite as an eco-friendly electrochemical sensor for the spasmolytic drug vincamine", Royal Society of Chemistry, 2026 More
Tweet