Development of a Liquid Chromatography-Negative ESI-Tandem Mass Spectrometry Method for Ibuprofen with Minimization of Matrix Effects Associated with Phospholipids

Faculty Pharmacy Year: 2008
Type of Publication: ZU Hosted Pages: 3194–3208
Authors:
Omnia Ahmed Emam Ismaiel
Journal: Journal of liquid chromatography USA Volume:
Keywords : Development , , Liquid Chromatography-Negative ESI-Tandem Mass Spectrometry Method    
Abstract:
Phospholipids are known to cause matrix ionization effects during LC=MS=MS analysis of biological samples. Matrix effects involving endogenous phospholipids in the negative ESI mode have been investigated in this work for the determinati
    
     
 
       

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