Monitoring phospholipids for assessment of matrix effects in a liquid chromatography–tandem mass spectrometry method for hydrocodone and pseudoephedrine in human plasma

Faculty Pharmacy Year: 2007
Type of Publication: ZU Hosted Pages: 84–93
Authors:
Omnia Ahmed Emam Ismaiel
Journal: Journal of Chromatography B USA Volume:
Keywords : Monitoring phospholipids , assessment , matrix effects , , liquid chromatography–tandem mass    
Abstract:
Matrix effects resulting in ion suppression or enhancement have been shown to be a source of variability and inaccuracy in bioanalytical mass spectrometry. Glycerophosphocholines may cause significant matrix ionization effects during quant
    
     
 
       

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