SYNTHESIS AND EVALUATION OF 2, 3-DIHYDROQUINAZOLIN-4(1H)-ONE DERIVATIVES AS ANALGESIC AND ANTI-INFLAMMATORY AGENTS

Faculty Pharmacy Year: 2013
Type of Publication: ZU Hosted Pages:
Authors:
Samy Megahed Ibrahiem Elsayed Sakr
Journal: Asian Journal of Research in Chemistry and Pharmaceutical Sciences ajrc Volume:
Keywords : SYNTHESIS , EVALUATION , , 3-DIHYDROQUINAZOLIN-4(1H)-ONE DERIVATIVES , ANALGESIC , ANTI-INFLAMMATORY AGENTS    
Abstract:
Applying internal Mannich reaction on N'-(substituted benzoyl)-2-(methyl- amino) benzohydrazide (IIa-h), under different conditions, afforded a new series of 2, 3-dihydroquinazolin-4(1H)-one derivatives (IIIa-g). The carbohydrazide; N'-(p
    
     
 
       

Author Related Publications

  • Samy Megahed Ibrahiem Elsayed Sakr, "Synthesis of New 2,3-Dihydroquinazolin-4(1H)-one Derivatives for Analgesic and Anti-inflammatory Evaluation", WILEY, 2010 More
  • Samy Megahed Ibrahiem Elsayed Sakr, "Synthesis of new benzotriazepin-5(2H)-one derivatives of expected antipsychotic activity", springer link, 2013 More
  • Samy Megahed Ibrahiem Elsayed Sakr, "Synthesis of Some New Benzisothiazolone and Benzenesulfonamide Derivatives of Biological Interest Starting from Saccharin Sodium", 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim, 2013 More
  • Samy Megahed Ibrahiem Elsayed Sakr, "Synthesis of Some New Benzisothiazolone and Benzenesulfonamide Derivatives of Biological Interest Starting from Saccharin Sodium", 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim, 2013 More
  • Samy Megahed Ibrahiem Elsayed Sakr, "Synthesis Of Certain -4-Quinazolones Likely To Possess Pharmacological Activity", لايوجد, 1900 More

Department Related Publications

  • Mansour Alsayed Mansour Abokol, "SPECTROPHOTOMETRIC DETERMINATION OF KETOPROFEN IN PHARMACEUTICAL PREPARATIONS BY MEANS OF CHARGE TRANSFER COMPLEXES", Talnta. Vol. 40. No. 4 pp. 585-588, 1993 More
  • Mansour Alsayed Mansour Abokol, "REACTION OF 2, 3- DICHLOROMALEIC ANHYDRIDE I: NITROSATIVE REDUCTIVE ELIMINATION; SYNTHESIS OF N-(2,6-DIMETHYLPHENYL)-2-(N-NITROSO-N-SUBSTITUTED)AMINO- SUCCINIMIDES", Chim. Farmaceutico – Anno 135 –pp.429-433 n. 7 Luglio/Agosto, 1996 More
  • Mansour Alsayed Mansour Abokol, "UTILITY OF DICHLOROMALEIMIDE DERIVATIVE AS CHROMOGENIC REAGENT FOR THE SPECTROPHOTOMETRIC DETERMINATION OF CERTAIN FLUOROQUINOLOINES AND RELATED COMPOUNDS", Mansour E.Abou Kull. Zagazig J.Pharm.sci., Dec.(1999) Vol.8 No.2, p13-17, 1999 More
  • Ahmed Samy Abdelsamad Abdelkhalek hilal, "Eco-friendly novel deconvoluted synchronous spectrofluorimetric approach for the determination of favipiravir, levodropropizine and moxifloxacin hydrochloride as an effective therapeutic combination for COVID-19; application in laboratory prepared mixtures and spiked human plasma", Elsevier, 2023 More
Tweet