labeling of some organic compounds of expected biological activity using radioiodine

The main objective of this thesis can be divided into three parts. The of optimum conditions for labeling of Colchicine (Col.) via electrophilic substitution reaction. The second part involves the electrophilic radioiodination of nitrofurantoin (NF). The 1-Electrophilic radioiodination of colchicine with iodine-125 is carried out. The reaction parameters studied were colchicine concentration, pH of the reaction mixture, reaction time, temperature, different oxidizing agents and different organic media to