An Immunological and Electrocardiographic Study on Carbon Tetrachloride Induced Toxicity in a Mammalian Animal

The present investigation aimed at exploring the immunological, haematological and electrocardiographic effects of CCl4 in adult male Sprague Dawely rats and the possible protective role of dimethyl sulphoxide (DMSO) against these effects if found.The immunological and haematological studies were carried out by measuring mixed leukocytes number, lymphocytes number, serum immunoglobulin M, interleukin-4, interleukin-6, red blood cells number, haemoglobin value , haematocrit percentage, mean corpuscuThe electrocardiographic study was carried out by measuring the heart rate and the QRS-complex amplitude following acute intraperitoneal injection of CCL4.