Synthesis and Conformational Analysis of Biologically Active Erythropoietin related peptides

Faculty Science Year: 2010
Type of Publication: Theses Pages:
Authors:
Al Sedik; Rasha Amin Amin
BibID 11011540
Keywords : Synthesis , Conformational Analysis , Biologically Active Erythropoietin    
Abstract:
The current study describes the synthesis of Erythropoietin-which is a prohibited hormone by WADA-mimetic peptides [(AFIII54(chain I), (Ser)12AFIII54(chain II), AFIII54 with addition of Gly and Tyr in position 4 and 5 respectively(chain VI) ,AFIII54 devoiConformational analysis using FT-IR spectroscopy showed that most the synthesised peptides existed in α-helix structure 
    
     
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