spectrophotometric and toxicological studies on some narcotic drugs

The monitoring of such drugs is important for quality assurance in preparations and for obtaining optimum therapeutic concentrations in body fluids to minimize the risk of toxicity. However, in the past decade, only limited studies have been performed on For toxicological studies; hundred and twelve mature albino rats of both sex (males and females) weighting 140 to 170 gm were used. Seven rats from each sex intraperitoneally administered (1, 1, 5 and 5 mg/kg B. wt) BZ, DZ, CPZ and THZ once daily for one