Synthesis of some nucleosides and evaluation of their biological activity

Pyrimidines are biologically active heterocyclic compounds; which share in the building of DNA and RNA, these compounds also called 1,3-diazines. The synthesis of pyrimidines was given attention from most of chemists, due to their interest as biologicallyPyrimidines are generally prepared by 7 types of ring closures (a-g) depending on the nature of the fragments which combine together to form the pyrimidine nucleus [Elderfield, 1966]..